... and cytoplasmic content (e.g. germ granules). mes-1 mutant embryos display the striking phenotype of transformation of P 4 into a muscle precursor, like its somatic sister. A loss of polarity in P 2 and P 3 cellspecific events underlies the Mes-1 phenotype. In mes-1 embryos, P 2 and P 3 undergo symmetric...

...Susan Strome,; Paula Martin,; Einhard Schierenberg; Janet Paulsen ABSTRACT Mutations in the maternal-effect sterile gene mes-1 cause the offspring of homozygous mutant mothers to develop into sterile adults. Lineage analysis revealed that mutant offspring are sterile because they fail to form...