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Keywords: MEK
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Journal Articles
Journal: Development
Development (2017) 144 (19): 3562–3577.
Published: 01 October 2017
... that regulate cartilage development. Here, we characterize a miRNA that promotes the biosynthesis of a key component in the RAF/MEK/ERK pathway in cartilage. Specifically, by transcriptome profiling we identified miR-322 to be upregulated during chondrocyte differentiation. Among the various miR-322 target...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (19): 3527–3537.
Published: 01 October 2007
... the anteroposterior axis, involving restricted ERK1/2 activation,was found to promote row I fates and repress row II fates. Our results reveal how the sequential integration of three signalling pathways - Nodal,Delta2/Notch and FGF/MEK/ERK - defines eight different sub-domains that characterise the ascidian caudal...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2003) 130 (1): 147–159.
Published: 01 January 2003
... nerve cord. The anterior part of the sensory vesicle comes from the a-line animal blastomeres, whereas the remaining CNS is largely derived from the A-line vegetal blastomeres. We have analysed the role of the Ras/MEK/ERK signalling pathway in the formation of the larval CNS in the ascidian, Ciona...