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Keywords: MEF2
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Journal Articles
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Journal: Development
Development (2016) 143 (5): 774–779.
Published: 1 March 2016
... of Biologists Ltd 2016 Summary: In the developing mouse anterior second heart field, the transcription factor MEF2C directly controls expression of the Nodal co-receptor Cripto to regulate outflow tract alignment. MEF2 Tdgf1 Cripto Enhancer Heart development Mouse Congenital heart...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (1): 31–42.
Published: 1 January 2013
... Lightning Chemiluminescent Reagent (Perkin Elmer). In vitro -translated mouse MEF2A (rabbit reticulocyte lysate; Promega) or nuclear extracts from C2C12 myotubes were used for gel shift assays. The mutant MEF2 site was generated in the same manner as the mutant Gtl2 reporter. Supershift assays...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (19): 3543–3552.
Published: 1 October 2012
...Zhimin Chen; Shanshan Liang; Ying Zhao; Zhe Han Mef2 is the key transcription factor for muscle development and differentiation in Drosophila . It activates hundreds of downstream target genes, including itself. Precise control of Mef2 levels is essential for muscle development as different Mef2...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (7): 1270–1275.
Published: 1 April 2012
... expression is the conserved transcription factor Mef2. In vivo, Mef2 is essential for the development of the Drosophila larval musculature: Mef2 -null embryos have no differentiated somatic muscle. By contrast, a similar phenotype has not been seen in analyses of the function of Mef2 genes in other examples...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (22): 4911–4919.
Published: 15 November 2011
... and insects, the transcription factor Mef2 plays a pivotal role in muscle differentiation; however, it is also an important regulator of neuron differentiation and survival. In the sea anemone Nematostella vectensis , an organism that lacks mesoderm but has muscles and neurons, Mef2 ( Nvmef2 ) has been...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (1994) 120 (5): 1251–1263.
Published: 1 May 1994
...Diane G. Edmondson; Gary E. Lyons; James F. Martin; Eric N. Olson ABSTRACT Members of the MEF2 family of transcription factors bind a conserved A/T-rich sequence in the control regions of many skeletal and cardiac muscle genes. To begin to assess the roles of the different Mef2 genes in the control...
Journal Articles
Journal: Development
Development (1993) 118 (4): 1095–1106.
Published: 1 August 1993
... muscle-specific genes. Among the participants in this process is the myocyte-specific enhancer factor 2 (MEF2) family of tissue-restricted transcription factors. These factors, which share a highly conserved DNA-binding domain including a MADS box, are essential for the expression of multiple muscle...