... EVT differentiation coincided with elevated transcriptomic levels of lysyl oxidase ( LOX ) in trophoblast anchoring columns, in which functional experiments established a role for LOX activity in promoting EVT column outgrowth. The findings of this work support a role for low oxygen in potentiating...

... emphasis has been placed on the factors required for the specification of the cells that comprise muscle, little is known about the crosstalk between them that enables the development of a patterned and functional tissue. We find in mice that deletion of lysyl oxidase (Lox), an extracellular enzyme...

... of Biologists Ltd 2014 Drosophila Human Mouse Glial cell migration PVR PDGF-receptor Lysyl oxidase Lox Extracellular matrix The formation of the brain is one of the most fascinating processes in development. Once neurons are born, they settle and never divide again. By contrast, glial...