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Keywords: Lunatic Fringe
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Journal Articles
Journal: Development
Development (2016) 143 (5): 822–830.
Published: 01 March 2016
...Dustin R. Williams; Emily T. Shifley; Kara M. Braunreiter; Susan E. Cole Vertebrate somitogenesis is regulated by a segmentation clock. Clock-linked genes exhibit cyclic expression, with a periodicity matching the rate of somite production. In mice, lunatic fringe ( Lfng ) expression oscillates...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (9): 1515–1522.
Published: 01 May 2010
... boundary formation. To clarify this discrepancy in our current study, we created a transgenic mouse lacking NICD boundaries in the anterior PSM but retaining Notch signal oscillation in the posterior PSM by manipulating the expression pattern of a Notch modulator, lunatic fringe. In this mouse, clearly...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (21): 3585–3595.
Published: 01 November 2009
... pronephric expression of lunatic fringe and radical fringe that is temporally and spatially appropriate for a role in regulating Notch signalling in the dorso-anterior region of the pronephros anlagen. On the basis of these results, along with data from previous publications, we propose a mechanism by which...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2008) 135 (5): 899–908.
Published: 01 March 2008
...Emily T. Shifley; Kellie M. VanHorn; Ariadna Perez-Balaguer; John D. Franklin; Michael Weinstein; Susan E. Cole The Notch pathway plays multiple roles during vertebrate somitogenesis,functioning in the segmentation clock and during rostral/caudal (R/C) somite patterning. Lunatic fringe ( Lfng...
Journal Articles
Journal: Development
Development (2005) 132 (4): 817–828.
Published: 15 February 2005
...Katherine L. Hahn; Joshua Johnson; Brian J. Beres; Sheena Howard; Jeanne Wilson-Rawls We have demonstrated that Notch genes are expressed in developing mammalian ovarian follicles. Lunatic fringe is an important regulator of Notch signaling. In this study, data are presented that demonstrate that...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2002) 129 (15): 3633–3644.
Published: 01 August 2002
... and epithelialized. We have further studied the molecular mechanisms underlying these interactions by focusing on Lunatic fringe, a modulator of Notch signaling, which is expressed in the region of the presumptive boundary. By combining DNA in ovo electroporation and embryonic transplantation...
Journal Articles
Journal: Development
Development (2002) 129 (5): 1107–1117.
Published: 01 March 2002
...Caroline Jouve; Tadahiro Iimura; Olivier Pourquie Vertebrate somitogenesis is associated with a molecular oscillator, the segmentation clock, which is defined by the periodic expression of genes related to the Notch pathway such as hairy1 and hairy2 or lunatic fringe (referred to as the cyclic...
Journal Articles
Journal: Development
Development (2001) 128 (24): 5139–5147.
Published: 15 December 2001
... counterparts are not able to organise themselves into somites and lose the expression of genes known to be important for vertebrate segmentation, such as Delta-1 , Notch-1 , paraxis , hairy1 , hairy2 and lunatic fringe . The digoxigenin or fluorescein-labelled RNA probes were produced as described previously...