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Keywords: Lumen formation
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Journal Articles
Journal: Development
Development (2016) 143 (10): 1663–1673.
Published: 15 May 2016
... epithelial architecture and lumen formation both in vivo and in three-dimensional (3D) primary cell cultures. Collectively, these results demonstrate that Blimp1 is required to maintain a highly proliferative luminal subset necessary for mammary gland development and homeostasis. * These authors...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (9): 1639–1650.
Published: 1 May 2015
... in the transverse plane, allowing sufficient time for lumen growth via an osmotic process along the longitudinal dimension. The dynamics of lumen formation is controlled by the TGFβ pathway and ROCK activity. Our findings reveal a TGFβ-ROCK-actomyosin contractility axis that coordinates lumen growth, which...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2013) 140 (13): 2776–2786.
Published: 1 July 2013
... findings not only identify a novel mechanism of vascular lumen formation, but also suggest a new form of developmental crosstalk between hematopoietic and endothelial cell lineages. * Author for correspondence ( wiebke.herzog@mpi-muenster.mpg.de ) Competing interests statement The authors...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (20): 4423–4432.
Published: 15 October 2011
.... , Mostov K. E. , Stainier D. Y. ( 2007 ). Genetic control of single lumen formation in the zebrafish gut . Nat. Cell Biol. 9 , 954 - 960 . Baye L. M. , Link B. A. ( 2008 ). Nuclear migration during retinal development . Brain Res. 1192 , 29 - 36 . Cervantes S...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (8): 1631–1641.
Published: 15 April 2011
... a mesenchymal-epithelial transition and form two apical domains at opposite ends. Extracellular lumens then form at the apical surfaces. We show that cortical actin and Ciona ezrin/radixin/moesin (ERM) are essential for lumen formation and that a polarized network of microtubules, which contributes to lumen...
Includes: Multimedia, Supplementary data