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Keywords: Lineage conversion
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Journal Articles
Journal: Development
Development (2020) 147 (4): dev183830.
Published: 17 February 2020
... neovascularization and cardiomyocyte survival. Additionally, we found that inhibition of one type of cell proliferation (namely, hepatocytes) induces the lineage conversion of another type cells (i.e. ductal cells) during tissue regeneration. These results validate the use of ip21-GFP mice as a new genetic tool...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (22): dev168617.
Published: 21 November 2018
... sequencing (RRBS). Despite major differences in methodology, lineage conversion and directed differentiation both produce cells that closely approximate the primary motor neuron state. However, we identify differences in Fas signaling, the Hox code and synaptic gene expression between lineage-converted...
Includes: Supplementary data