1-20 of 74
Keywords: Limb development
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles
Journal: Development
Development (2022) 149 (9): dev200340.
Published: 12 May 2022
.... WNT7A and RECK have been shown previously to play a role in limb development, but the mechanism of RECK action in this context is unknown. The roles of WNT7B and GPR124 in limb development have not been investigated. Using combinations of conventional and/or conditional loss-of-function alleles...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (5): dev200282.
Published: 11 March 2022
...Takashi Takeuchi; Haruka Matsubara; Fumina Minamitani; Yukio Satoh; Sayo Tozawa; Tomoki Moriyama; Kohei Maruyama; Ken-ichi T. Suzuki; Shuji Shigenobu; Takeshi Inoue; Koji Tamura; Kiyokazu Agata; Toshinori Hayashi ABSTRACT The 5′Hox genes play crucial roles in limb development and specify regions...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (23): dev200182.
Published: 3 December 2021
.... and Crenshaw , E. B. III . ( 2001 ). BMPR-IA signaling is required for the formation of the apical ectodermal ridge and dorsal-ventral patterning of the limb . Development 128 , 4449 - 4461 . 10.1242/dev.128.22.4449 Anders , S. , Pyl , P. T. and Huber , W. ( 2015 ). HTSeq...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (19): dev180042.
Published: 5 October 2020
... chromatid segregation and promoting daughter cell intercalations that shape the early limb bud. Iroquois Cohesin Limb development Mesodermal cell intercalations Mitotic chromatid segregation Morphogenesis Iroquois (Irx) genes were first identified as regulators of pre-pattern that control...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (21): dev190967.
Published: 14 August 2020
... syndrome, and Lowry-Wood syndrome. Similarly, primordial dwarfism in domesticated animals is linked to positive selection in minor spliceosome components. Despite being vital for limb development and size regulation, its role remains unexplored. Here, we disrupt minor spliceosome function in the developing...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (7): dev158550.
Published: 9 April 2018
... interactions may have limited predictive value for identifying enhancer mutations with strong loss-of-function phenotypes during development. Enhancer-promoter interactions Genomics Limb development Enhancer loss-of-function mutations Embryonic development depends on the spatial, temporal...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (7): dev161208.
Published: 29 March 2018
.../ Summary: Global profiling of five transcription factors associated with connective tissue subtypes reveals molecular signatures regulated during limb development and provides a data resource for future studies of connective tissue formation. Chicken model Limb development Connective tissue...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (3): dev160093.
Published: 8 February 2018
... Highlighted Article: The mutation in the PMA mouse model of human clubfoot was mapped and a candidate gene, Limk1 , identified that was shown to cause sciatic nerve and limb abnormalities when overexpressed. Limk1 Axon guidance Clubfoot Limb development Chicken Congenital talipes...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (1): dev157412.
Published: 8 January 2018
... Uhrf1 is known to be a key molecule for the maintenance of DNA methylation, and its role in cell proliferation is important for progression of some cancers. However, the functional role of Uhrf1 in other processes, such as limb development, is unknown. In this study, we generated limb mesenchymal cell...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (13): 2480–2489.
Published: 1 July 2017
... . Development   131 , 299 - 309 . 10.1242/dev.00936 Charite , J. , Mcfadden , D. G. and Olson , E. N. ( 2000 ). The bHLH factor dHAND controls sonic hedgehog expression and establishment of the zone of polarizing activity during limb development . Development   127 , 2461 - 2470...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (3): 479–486.
Published: 1 February 2017
...Patricia Saiz-Lopez; Kavitha Chinnaiya; Matthew Towers; Maria A. Ros ABSTRACT An intrinsic timing mechanism specifies the positional values of the zeugopod (i.e. radius/ulna) and then autopod (i.e. wrist/digits) segments during limb development. Here, we have addressed whether this timing mechanism...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (24): 4608–4619.
Published: 15 December 2016
.... , Harris , M. P. , Simandl , B. K. , Li , Y. , Beachy , P. A. and Fallon , J. F. ( 2001 ). Manifestation of the limb prepattern: limb development in the absence of Sonic hedgehog function . Dev. Biol.   236 , 421 - 435 . 10.1006/dbio.2001.0346 Cooper , K. L. , Hu , J...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (19): 3491–3505.
Published: 1 October 2016
... Crawford , K. and Stocum , D. L. ( 1988a ). Retinoic acid proximalizes level-specific properties responsible for intercalary regeneration in axolotl limbs . Development   104 , 703 - 712 . Crawford , K. and Stocum , D. L. ( 1988b ). Retinoic acid coordinately proximalizes...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (16): 2994–3001.
Published: 15 August 2016
... that, during mouse limb development, enhancer-driven gene expression results in the juxtaposition of Shh and its limb bud-specific enhancer only within cells of the distal posterior limb bud. 5C Chromosome loop Enhancer Limb development Super-resolution microscopy Chromatin looping...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (9): 1672–1683.
Published: 1 May 2015
.... Limb development is a well-studied topic in vertebrate organogenesis. Nevertheless, there is still little understanding of tissue-level deformation relative to molecular and cellular dynamics. This is mainly because live recording of detailed cell behaviors in whole tissues is technically difficult...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (4): 672–680.
Published: 15 February 2015
...Idit Eshkar-Oren; Sharon Krief; Napoleone Ferrara; Alison M. Elliott; Elazar Zelzer Blood vessels serve as key regulators of organogenesis by providing oxygen, nutrients and molecular signals. During limb development, programmed cell death (PCD) contributes to separation of the digits...
Journal Articles
Journal: Development
Development (2014) 141 (9): 1906–1914.
Published: 1 May 2014
... 3 3 2014 © 2014. Published by The Company of Biologists Ltd 2014 Enhancer Gli Gremlin Limb development Silencer Sonic Hedgehog Mouse The Hedgehog (Hh) pathway is one of the primary signaling mechanisms underlying developmental patterning in organisms ranging from...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (8): 1715–1725.
Published: 15 April 2014
... unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed. Sonic hedgehog Long-range regulation ZRS Limb development Mouse * Author for correspondence ( bob.hill@igmm.ed.ac.uk ) Competing interests The authors declare...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (22): 4574–4582.
Published: 15 November 2013
... regulators of skeletal morphology as previously thought, but are key factors that regulate regional patterning and integration of the musculoskeletal system. 20 3 2013 22 8 2013 © 2013. Published by The Company of Biologists Ltd 2013 Hox genes Limb development Stromal cells...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (10): 2130–2138.
Published: 15 May 2013
...Rushikesh Sheth; Damien Grégoire; Annie Dumouchel; Martina Scotti; Jessica My Trang Pham; Stephen Nemec; Maria Félix Bastida; Marian A. Ros; Marie Kmita Limb development relies on an exquisite coordination between growth and patterning, but the underlying mechanisms remain elusive. Anterior...
Includes: Supplementary data