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Keywords: Ligand-dependent transactivation
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Journal Articles
Bénédicte Mascrez, Manuel Mark, Andrée Dierich, Norbert B. Ghyselinck, Philippe Kastner, Pierre Chambon
Journal:
Development
Development (1998) 125 (23): 4691–4707.
Published: 1 December 1998
...) of the ligand-binding domain (LBD), and includes the core of the Activating Domain of the Activation Function 2 (AF-2 AD core) that is thought to be crucial in mediating ligand-dependent transactivation by RXRα. The homozygous mutants (RXRα af2 o ), which die during the late fetal period or at birth, exhibit...
