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Keywords: Lifespan
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Journal Articles
Journal: Development
Development (2006) 133 (4): 611–619.
Published: 15 February 2006
...Patrick Narbonne; Richard Roy In C. elegans , reduced insulin-like signalling induces developmental quiescence, reproductive delay and lifespan extension. We show here that the C. elegans orthologues of LKB1 and AMPK cooperate during conditions of reduced insulin-like signalling to establish cell...
Journal Articles
Journal: Development
Development (2003) 130 (6): 1089–1099.
Published: 15 March 2003
... are grossly normal in morphology and development, grow longer to be almost twice as big,and have weak egg-laying defects and extended lifespan. All the four mutants have a mutation in the egl-4 gene. We show that the egl-4 gene encodes cGMP-dependent protein kinases. egl-4 promoter::gfp fusion genes...
Journal Articles