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Keywords: Lhx9
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Journal Articles
Journal: Development
Development (2015) 142 (6): 1113–1124.
Published: 15 March 2015
... neurons in vivo , we identified the LIM homeobox transcription factor Lhx9 as necessary and sufficient to specify Hcrt neurons. We found that Lhx9 can directly induce hcrt expression and we identified two potential Lhx9 binding sites in the zebrafish hcrt promoter. Akin to its function in zebrafish, we...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (2): 389–398.
Published: 15 January 2014
... and granule cells. We use a combination of in vitro explant culture, genetic fate mapping and gene overexpression and knockdown to explore the role of isthmic signalling in patterning these domains. We show that an FGF-dependent isthmic Atoh1 domain is the origin of distinct populations of Lhx9 -positive...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2009) 136 (8): 1375–1385.
Published: 15 April 2009
..., it is unknown how these signaling interactions are processed in the responding cells. We have found that distinct LIM homeodomain transcription factors, encoded by the LIM homeobox(LIM-HD) genes Lhx2, Lhx9 and Lmx1b integrate the signaling events that link limb patterning and outgrowth along all three axes...
Includes: Supplementary data