...Nicolas Fossat; Chi Kin Ip; Vanessa J. Jones; Joshua B. Studdert; Poh-Lynn Khoo; Samara L. Lewis; Melinda Power; Karin Tourle; David A. F. Loebel; Kin Ming Kwan; Richard R. Behringer; Patrick P. L. Tam ABSTRACT Lhx1 encodes a LIM homeobox transcription factor that is expressed in the primitive...

... of the embryonic head of the Otx2 null mutant. Expression of Dkk1 and Lhx1 , two genes that are also essential for head formation, is disrupted in the AME of the conditional Otx2 -deficient embryos. Consistent with the fact that Dkk1 is a direct target of OTX2, we showed that OTX2 can interact with the H1...

...Yuuri Yasuoka; Masaaki Kobayashi; Daisuke Kurokawa; Koji Akasaka; Hidetoshi Saiga; Masanori Taira Expression of the LIM homeobox gene lhx1 ( lim1 ) is specific to the vertebrate gastrula organizer. Lhx1 functions as a transcriptional regulatory core protein to exert `organizer' activity in Xenopus...

...Andrea Pillai; Ahmed Mansouri; Richard Behringer; Heiner Westphal; Martyn Goulding Lhx1 and Lhx5 are co-expressed in multiple interneuron cell types in the developing spinal cord. These include early-born dI4 and dI6 inhibitory interneurons, as well as late-born inhibitory dIL A neurons (dIL...

... reproductive tract. * Author for correspondence (e-mail: [email protected] ) 18 4 2005 ©2005. 2005 Lhx1 Lim1 Mesonephros Metanephros Müllerian duct Development of the kidney is one of the best-studied processes of vertebrate organogenesis ( Grobstein,1953 ; Grobstein...