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Keywords: Leukemia
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Journal Articles
AML1-ETO reprograms hematopoietic cell fate by downregulating scl expression
Available to PurchaseJing-Ruey J. Yeh, Kathleen M. Munson, Yvonne L. Chao, Quinn P. Peterson, Calum A. MacRae, Randall T. Peterson
Journal:
Development
Development (2008) 135 (2): 401–410.
Published: 15 January 2008
...Jing-Ruey J. Yeh; Kathleen M. Munson; Yvonne L. Chao; Quinn P. Peterson; Calum A. MacRae; Randall T. Peterson AML1-ETO is one of the most common chromosomal translocation products associated with acute myelogenous leukemia (AML). Patients carrying the AML1-ETO fusion gene exhibit an accumulation...
Includes: Supplementary data
Journal Articles
Runx1 is required for zebrafish blood and vessel development and expression of a human RUNX1-CBF2T1 transgene advances a model for studies of leukemogenesis
Available to PurchaseMaggie L. Kalev-Zylinska, Julia A. Horsfield, Maria Vega C. Flores, John H. Postlethwait, Maria R. Vitas, Andrea M. Baas, Philip S. Crosier, Kathryn E. Crosier
Journal:
Development
Development (2002) 129 (8): 2015–2030.
Published: 15 April 2002
... leukemias. Consequently, the normal function of RUNX1 and its involvement in leukemogenesis remain subject to intensive research. To further elucidate the role of RUNX1 in hematopoiesis, we cloned the zebrafish ortholog ( runx1 ) and analyzed its function using this model system. Zebrafish runx1...
