...Carlos Estella; Richard S. Mann Drosophila leg development requires the cooperation of two secreted signals, Decapentaplegic (Dpp) and Wingless (Wg), to form the proximodistal (PD) axis. Wg and Dpp are also required to pattern the dorsoventral (DV) axis of the leg. Here, we show that Distalless...

... of the leg-specification mechanism explains several mutant phenotypes, previously described in D. melanogaster , and suggests a mechanism for the evolution of legs from a ground state. Oncopeltus fasciatus tiptop Antennapedia Leg development Ground state RNA-interference The diversity...

... a molecular framework for understanding how segmentation during tissue growth is accomplished. e-mail: [email protected] 29 8 2001 © 2001. 2001 Leg development Segmentation Drosophila Serrate Delta fringe homothorax dachshund Distal-less...

...Takuya Tsuji; Atsushi Sato; Ichiro Hiratani; Masanori Taira; Kaoru Saigo; Tetsuya Kojima ABSTRACT During Drosophila leg development, the distal-most compartment (pretarsus) and its immediate neighbour (tarsal segment 5) are specified by a pretarsus-specific homeobox gene, aristaless , and tarsal...

..., implying that temporal and spatial regulations of the dpp gene expression are closely correlated with morphological diversity. In conclusion, although leg developmental pathways are different among insect species, the principal mechanism of leg development is likely to be conserved, judged from...

...Elizabeth L. Jockusch; Candice Nulsen; Stuart J. Newfeld; Lisa M. Nagy ABSTRACT All insect legs are structurally similar, characterized by five primary segments. However, this final form is achieved in different ways. Primitively, the legs developed as direct outgrowths of the body wall...

... of Biologists 1999 Drosophila melanogaster Leg development Proximodistal axis escargot homothorax Patterning in insect legs is organized along anteroposterior (AP), dorsoventral (DV) and proximodistal (PD) axes. In the case of Drosophila , AP and DV axes of the leg imaginal discs...

... of Biologists 1999 Drosophila melanogaster Serrate Delta Notch Leg development Signalling Animal development involves many types of cell communication processes and the molecular bases of some of these processes have been unravelled in recent years. An unexpected finding has been...

..., Serrate and Suppressor of Hairless , also participate in Notch function during leg development, and their expression is localised within the leg segments with respect to segment boundaries. The failure to form joints when Notch signalling is compromised leads to shortened legs, suggesting that the correct...

..., ubiquitous expression of exd does not appear to have morphological consequences. 09 August 1995 © 1995 by Company of Biologists 1995 extradenticle homeotic transformation clonal analysis Drosophila pattern formation leg development In Drosophila , development...