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Keywords: Left-right asymmetry
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Journal Articles
Journal: Development
Development (2021) 148 (17): dev199265.
Published: 06 September 2021
... and gut left-right asymmetry . Development 127 , 3567 - 3579 . 10.1242/dev.127.16.3567 Bolger , A. M. , Lohse , M. and Usadel , B. ( 2014 ). Trimmomatic: a flexible trimmer for Illumina sequence data . Bioinformatics 30 , 2114 - 2120 . 10.1093/bioinformatics/btu170...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (19): dev187583.
Published: 12 October 2020
... by The Company of Biologists Ltd 2020 Summary: This Review aims to shed new light on the development of laterality in the stomach and intestine, challenging classical models of left-right asymmetric gut morphogenesis. Gut tube Intestine Laterality Left-right asymmetry Morphogenesis Stomach...
Journal Articles
Journal: Development
Development (2020) 147 (1): dev182469.
Published: 13 January 2020
.... Cell Biol.   6 , 306 - 317 . 10.1038/nrm1622 Hu , G. , Li , G. , Wang , H. and Wang , Y. ( 2017 ). Hedgehog participates in the establishment of left-right asymmetry during amphioxus development by controlling Cerberus expression . Development   144 , 4694 - 4703...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (12): dev180398.
Published: 14 June 2019
.... We also uncovered evidence for defects in left-right asymmetry within atrial cardiomyocyte populations. Furthermore, we were able to detail defects in cardiac outflow tract and valve development associated with Pitx2 . Our findings offer insight into Pitx2 function and provide a compilation of gene...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (9): dev173575.
Published: 10 May 2019
... induces and patterns the frog left-right organizer in the early gastrula and regulates the morphogenesis of the flow sensor following specification of the precursor tissue. FGF Pkd2 Sprouty Left-right asymmetry Leftward flow LRO Left-right (LR) asymmetry of inner organs is present...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (22): dev162776.
Published: 22 November 2018
... compares mechanisms underlying asymmetric heart morphogenesis and the dynamics thereof in fish, chick and mouse, relating them to clinical presentations and providing an evolutionary perspective. Heart looping Heart morphogenesis Heterotaxy Left-right asymmetry The heart is an asymmetric...
Journal Articles
Journal: Development
Development (2017) 144 (24): 4694–4703.
Published: 15 December 2017
... . Development   138 , 4819 - 4830 . 10.1242/dev.066720 Boorman , C. J. and Shimeld , S. M. ( 2002 ). Pitx homeobox genes in Ciona and amphioxus show left-right asymmetry is a conserved chordate character and define the ascidian adenohypophysis . Evol. Dev.   4 , 354 - 365 . 10.1046/j.1525...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (23): 4068–4079.
Published: 01 December 2015
... interaction with Nup98, in the Xenopus left-right organizer. Nek2 Cilia Congenital heart disease Left-right asymmetry Nucleoporin The vertebrate left-right (LR) axis is the last body axis to be established, after the anteroposterior and dorsoventral axes. Thus, LR asymmetry presents...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (8): 1603–1613.
Published: 15 April 2014
... predict, induces the asymmetric Nodal cascade. Cilia Evolution Left-right asymmetry Left-right organizer Leftward flow Symmetry is a guiding principle for the construction of animal body plans. Apart from sponges, which are considered the most basal branch of the animal phylogenetic tree...
Journal Articles
Journal: Development
Development (2013) 140 (22): 4465–4470.
Published: 15 November 2013
... summarize here, leaders in the field gathered at the symposium to discuss recent advances in understanding how left-right asymmetry is generated and utilized across the animal kingdom. * Authors for correspondence ( rburdine@princeton.edu ; tcaspar@emory.edu ) Competing interests The authors...
Journal Articles
Journal: Development
Development (2013) 140 (7): 1550–1559.
Published: 01 April 2013
... giant larvae 2 ( lgl2 ) is expressed prominently in ciliated organs. Lgl proteins are involved in establishing cell polarity and have been implicated in vesicle trafficking. Here, we identified a role for Lgl2 in development of ciliated epithelia in Kupffer’s vesicle, which directs left-right asymmetry...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (23): 4439–4448.
Published: 01 December 2012
... by The Company of Biologists Ltd 2012 Autotaxin Lysophosphatidic acid Calcium Left-right asymmetry Zebrafish We thank Drs Sheng-Ping Huang, Dr Wen-Pin Wang and Chin-Hwa Hu and Taiwan Zebrafish core facility for providing technical guidance, plasmids and reagents, in particular Dr Sheng-Ping...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (18): 3257–3262.
Published: 15 September 2012
... indispensable for left-right asymmetry in Xenopus and chick ( Adams et al., 2006 ). In the chick, asymmetric localization of H + /K + -ATPaseα mRNA is apparent at Hensen’s node and is required for the subsequent establishment of Sonic hedgehog (Shh) asymmetric gene expression ( Aw et al., 2008 ). However...
Journal Articles
Journal: Development
Development (2012) 139 (13): 2426–2435.
Published: 01 July 2012
... interests. 22 4 2012 © 2012. Left-right asymmetry Endoderm Gap junction Sox17 Nodal Establishing a three-dimensional axis, with anteroposterior, dorsoventral and left-right (LR) coordinates, is a critical step in embryogenesis. LR axis determination provides...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (11): 2009–2019.
Published: 01 June 2012
...@mail.tsinghua.edu.cn ) Competing interests statement The authors declare no competing financial interests. 19 3 2012 © 2012. Zebrafish Left-right asymmetry Wnt β-Catenin Nodal Regardless of symmetric external appearance, vertebrates have left-right (LR) asymmetric...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (10): 1874–1884.
Published: 15 May 2012
... no competing financial interests. 6 3 2012 © 2012. DE-Cadherin Left-right asymmetry Myo31DF Myosin IC Myosin ID Shotgun Drosophila Myo61F L/R patterning is required for the functional organization of the body plan and the L/R asymmetric development...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (8): 1467–1475.
Published: 15 April 2012
...Kazuhiko Nishide; Michio Mugitani; Gaku Kumano; Hiroki Nishida Tadpole larvae of the ascidian Halocynthia roretzi show morphological left-right asymmetry. The tail invariably bends towards the left side within the vitelline membrane. The structure of the larval brain is remarkably asymmetric. nodal...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (20): 4405–4410.
Published: 15 October 2011
... in all vertebrates. * Author for correspondence ( rburdine@princeton.edu ) Competing interests statement The authors declare no competing financial interests. 12 8 2011 © 2011. nodal southpaw Zebrafish Bmp Left-right asymmetry Midline barrier lefty...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (16): 3509–3518.
Published: 15 August 2011
... statement The authors declare no competing financial interests. 10 6 2011 © 2011. C. elegans Microtubules Olfactory development Left-right asymmetry Calcium signaling The left and right sides of the central nervous system display anatomical, molecular...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (9): 1817–1826.
Published: 01 May 2011
... of endoderm formation and left-right asymmetry during early zebrafish development and provide the first evidence for a regulatory function for gata5 in the formation of Kupffer's vesicle and left-right patterning. * Author for correspondence ( james.g.patton@vanderbilt.edu ) Competing interests...
Includes: Supplementary data