..., which affect osmolarity of their cells and consequently cellular function. Mechanosensory lateral line hair cells detect water motion for swimming behavior and are especially susceptible to salinity changes due to their direct contact with the environment. To maintain hair cell function when salinity...

... to distill cell and nuclear shape variation into discrete biologically meaningful parameters. We apply these methods to analyze shape in the neuromast cells of the zebrafish lateral line system, finding that shapes vary with cell location and identity. The distinction between hair cells and support cells...

... with plasticity in form during evolution. Further work is needed to understand how both cell-extrinsic and cell-intrinsic processes produce the vast array of MMP-derived muscles found in vertebrates. Such studies may also shed light on how other cell types migrate, such as the lateral line that we show requires...

... that result in parallel sensory lines in medaka embryos. A ventral posterior lateral line (pLL) is composed of neuromasts deposited by collectively migrating cells whereas a midline pLL is formed by individually migrating cells. Despite the variable number of neuromasts among embryos, the sequential...

...Damian Dalle Nogare; Katherine Somers; Swetha Rao; Miho Matsuda; Michal Reichman-Fried; Erez Raz; Ajay B. Chitnis Collective migration of cells in the zebrafish posterior lateral line primordium (PLLp) along a path defined by Cxcl12a expression depends on Cxcr4b receptors in leading cells...

... lateral line primordium (pLLP), a cohort of ∼100 cells that collectively migrate along the trunk of the zebrafish embryo. The pLLP comprises proliferative progenitor cells and organized epithelial cells that will form the mechanosensory organs of the posterior lateral line. Wnt signaling is active...

... no competing financial interests. 24 7 2013 19 1 2014 © 2014. Published by The Company of Biologists Ltd 2014 Collective migration Morphogenesis Microtubules Cell adhesion Lateral line Zebrafish The coordinated remodelling of epithelial sheets drives...

...Miho Matsuda; Damian Dalle Nogare; Katherine Somers; Kathleen Martin; Chongmin Wang; Ajay B. Chitnis The posterior lateral line primordium (PLLp) migrates caudally and periodically deposits neuromasts. Coupled, but mutually inhibitory, Wnt-FGF signaling systems regulate proto-neuromast formation...

.... Yet, how pattern information is used to orchestrate these different processes is still unclear. During lateral line (LL) morphogenesis, a group of cells simultaneously migrate and assemble radially organized cell clusters, termed rosettes, that prefigure LL sensory organs. This process is controlled...

... that regulate proliferation. In the migrating posterior lateral line primordium (PLLP), proliferation is predominantly localised to the leading zone. As cells emerge from this zone, they periodically organise into rosettes that subsequently dissociate from the primordium and differentiate as neuromasts. Despite...

...Nicolas Gompel; Christine Dambly-Chaudière; Alain Ghysen ABSTRACT The central projection of the fish lateral line displays somatotopic ordering. In order to know when and how this ordering is established, we have labelled single sensory neurones and followed the growth of their neurites. We show...

... of a specific set of sensory neurons, the posterior ganglion of the lateral line, in zebrafish. To examine the in vivo action of this molecule, we analyzed (1) the pathways followed by lateral line growth cones in mutants in which the expression of sema Z1a is altered in an interesting way, (2) response...

... derivatives (pigment cells and/or cartilaginous elements of the jaw). At least one mutant, dog-eared , shows defects in both the ear and another placodally derived sensory system, the lateral line, while hypersensitive mutants have additional trunk lateral line organs. * Author for correspondence (e...