..., Tennis Court Road, Cambridge CB2 1QR,UK 14 12 2005 © 2006. 2006 Dorsal aorta Skeletal muscle Smooth muscle Clonal analysis LaacZ Pax3 The dorsal aorta in amniotes is an early embryonic blood vessel composed of endothelial and smooth muscle cells. It is also...

... 2 5 2003 © 2003. 2003 Mouse heart morphogenesis Myocardium Clonal cell growth laacZ The heart, which is the first organ to form in the embryo, provides a striking example of morphogenesis (see Harvey, 2002 ). The cardiac precursor cells invaginate early through...

...Sophie Eloy-Trinquet; Jean-François Nicolas In this study, we investigated (in the early mouse embryo) the clonal properties of precursor cells which contribute to the segmented myotome, a structure derived from the somites. We used the laacZ method of single cell-labelling to visualise clones...

... precursor cells during segmentation of the paraxial mesoderm and myotome formation, using mouse LaacZ/LacZ chimeras. We demonstrate that precursors of medial and lateral myotomes are clonally separated in the mouse somite, consistent with earlier studies in birds. This clonal separation occurs after...

...Luc Mathis; Jean François Nicolas ABSTRACT We have performed a systematic clonal analysis to describe the modes of growth, dispersion and production of cells during the development of the mouse neural system. We have used mice expressing a LaacZ reporter gene under the control of the neuron...

...Luc Mathis; Johan Sieur; Octavian Voiculescu; Patrick Charnay; Jean-François Nicolas ABSTRACT We made use of the laacz procedure of single-cell labelling to visualize clones labelled before neuromere formation, in 12.5-day mouse embryos. This allowed us to deduce two successive phases of cell...

... domains observed in this study and that the cellular and genetic organisation of the cerebellum are coordinated. * Author for correspondence 04 08 1997 © 1997 by Company of Biologists 1997 cell lineage cerebellum clonal analysis clonal growth compartment founder cell LaacZ...

... by intragenic homologous recombination in transgenic mice expressing a reporter laacZ gene. 153 clones corresponding to 7829 cells, that is 20% of the myotomal population of one embryo, were obtained from 3000 E11.5 embryos. Their analysis leads to the hypothesis that, at E11.5, the 41 segments of the myotome...