... markers of ectoderm. To gain insight into how ectoderm is specified, we looked for candidate ectoderm-specific genes that are ectopically expressed in VegT-depleted embryos, and examined the role of one of these, the LIM homeobox gene Xlim5 , in ectoderm development. We show that overexpression of Xlim5...

... and temporal cues that are required for the precise regulation of zig gene expression. We find that two LIM homeobox genes, the Lhx3 -class gene ceh-14 and the Lmx-class gene lim-6 are coordinately required for zig gene expression in PVT. Temporal control of zig gene expression is conferred...

...Trina R. Sarafi-Reinach; Tali Melkman; Oliver Hobert; Piali Sengupta Chemosensory neuron diversity in C. elegans arises from the action of transcription factors that specify different aspects of sensory neuron fate. In the AWB and AWA olfactory neurons, the LIM homeobox gene lim-4 and the nuclear...

...Oliver Hobert; Kristin Tessmar; Gary Ruvkun We describe here the functional analysis of the C. elegans LIM homeobox gene lim-6 , the ortholog of the mammalian Lmx-1a and b genes that regulate limb, CNS, kidney and eye development. lim-6 is expressed in a small number of sensory-, inter...

... Mandible Lim homeobox Fgf-8 Goosecoid Mouse Cell signalling The establishment of pattern during embryogenesis involves the cellular and molecular division of cells to provide ‘positional information’. Branchial arches give rise to a wide range of structures specific to each arch. Thus each...

...Forbes D. Porter; John Drago; Yang Xu; Surindar S. Cheema; Chris Wassif; Sing-Ping Huang; Eric Lee; Alexander Grinberg; Jim S. Massalas; David Bodine; Frederick Alt; Heiner Westphal ABSTRACT We investigated the function of Lhx2 , a LIM homeobox gene expressed in developing B-cells, forebrain...