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Keywords: LIF
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Journal Articles
Journal: Development
Development (2015) 142 (20): 3488–3499.
Published: 15 October 2015
...Sophie M. Morgani; Joshua M. Brickman Embryonic stem cells (ESCs) are pluripotent cell lines that can be maintained indefinitely in an early developmental state. ESC culture conditions almost always require the cytokine LIF to maintain self-renewal. As ESCs are not homogeneous but contain multiple...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (23): 4457–4467.
Published: 1 December 2014
... embryonic germ cells (EGCs) in culture in the presence of particular extracellular factors, such as combinations of Steel factor (KITL), LIF and bFGF (FGF2). Early PGCs form EGCs more readily than do later PGCs, and PGCs lose the ability to form EGCs by embryonic day (E) 15.5. Here, we examined the effects...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (16): 3311–3322.
Published: 15 August 2013
...Marie-Emmanuelle Mathieu; Corinne Faucheux; Claire Saucourt; Fabienne Soulet; Xavier Gauthereau; Sandrine Fédou; Marina Trouillas; Nadine Thézé; Pierre Thiébaud; Hélène Boeuf Pluripotent mouse embryonic stem cells (mESCs), maintained in the presence of the leukemia inhibitory factor (LIF) cytokine...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2003) 130 (18): 4287–4294.
Published: 15 September 2003
... primordial follicle development and initiates folliculogenesis. Mol. Cell. Endocrinol. 175 , 123 -130. Nilsson, E. E., Kezele, P. and Skinner, M. K. ( 2002 ). Leukemia inhibitory factor (LIF) promotes the primordial to primary follicle transition in rat ovaries. Mol. Cell. Endocrinol. 188 , 65 -73...
Journal Articles
Journal: Development
Development (2003) 130 (15): 3459–3468.
Published: 1 August 2003
...Ekaterini A. Kritikou; Andrew Sharkey; Kathrine Abell; Paul J. Came; Elizabeth Anderson; Richard W. E. Clarkson; Christine J. Watson STAT3 is the key mediator of apoptosis in mammary gland. We demonstrate here that LIF is the physiological activator of STAT3, because in involuting mammary glands...
Journal Articles
Journal: Development
Development (2003) 130 (11): 2505–2512.
Published: 1 June 2003
...Koji Shimozaki; Kinichi Nakashima; Hitoshi Niwa; Tetsuya Taga Oct3/4 plays a critical role in maintaining embryonic stem cell pluripotency. Regulatable transgene-mediated sustained Oct3/4 expression in ES cells cultured in serum-free LIF-deficient medium caused accelerated differentiation...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2003) 130 (3): 611–622.
Published: 1 February 2003
..., cortical infusion of the cytokine LIF, which affects development of visual cortex neurochemical architecture, transiently inhibited growth of neurons in LGN,cortical layer IV and VI and SGS. In summary, the study presents three important results. First, central neurons regulate soma size development...
Journal Articles
Journal: Development
Development (2002) 129 (6): 1387–1396.
Published: 15 March 2002
... expression in sympathetic neurons. *Author for correspondence (e-mail: rohrer@mpih-frankfurt.mpg.de ) 20 12 2001 © 2002. 2002 LIF Cytokine Transmitter Plasticity Chick Noradrenergic Cholinergic VIP During development, a large variety of different neuronal phenotypes...