... for NrCAM in the navigation of RGC axons in the developing retina towards the optic fissure, and also for pathfinding into the optic nerve. NrCAM Axonal CAMs L1 Axon navigation Embryonic retina Central nervous system development Time-lapse 3D reconstruction Axonal pathfinding during...

... is restricted to the L1 cell layer of most meristems and organ primordia, including those of the ovule integuments. Insertion mutations show that ARABIDOPSIS CRINKLY4 is required for regulation of cellular organisation during the development of sepal margins and ovule integument outgrowth. We show...

...Mitsutomo Abe; Hiroshi Katsumata; Yoshibumi Komeda; Taku Takahashi In higher plants, the outermost cell layer (L1) of the shoot apex gives rise to the epidermis of shoot organs. Our previous study demonstrated that an 8-bp motif named the L1 box functions as a cis-regulatory element for L1-specific...

... of these neurons occurs along the TAG-1-expressing axons of the developing corticofugal system. The spatial and temporal pattern of expression of TAG-1 on corticofugal fibers coincides with the order of appearance of GABAergic cells in the developing cortex. Blocking the function of TAG-1, but not of L1, another...

... in a 1:2000 dilution of an anti-L1 rabbit polyclonal antibody (a gift from C. Lagenaur). Sections were rinsed in PBS, incubated for 1 hour in a 1:200 dilution of biotin-conjugated anti-rabbit IgG (Vector) and rinsed again. To quench endogenous peroxidase activity, sections were incubated in 0.5% H 2 O 2...