... leaflet maturation remains poorly understood. Here, we show in mouse that neural crest cells from pre-otic and post-otic regions make distinct contributions to the arterial valve leaflets. Genetic fate-mapping analysis of Krox20-expressing neural crest cells shows a large contribution to the borders...

... pathways, and exposure of the cells to pertinent growth factors led to the expression of the Schwann cell markers SOX10, KROX20 (EGR2), p75NTR (NGFR), MBP and S100B by day 4 in virtually all cells, and maturation was completed by 2 weeks of differentiation. Gene expression profiling demonstrated expression...

... unclear how these signals are integrated to specify discrete tissue territories. Here, we investigate the molecular mechanisms underlying the formation of one of the hindbrain segments, rhombomere (r) 3, specified by the expression of the gene krox20 . Dissecting krox20 transcriptional regulation has...

... signals to activate valentino and krox20 expression. Second, vhnf1 functions independently of Fgf signals to repress hoxb1a expression. Although vhnf1 is expressed in a broad posterior domain during gastrulation, it promotes the specification of individual rhombomeres. This is achieved in part because...

...Giselbert Hauptmann; Heinz-Georg Belting; Uta Wolke; Karen Lunde; Iris Söll; Salim Abdelilah-Seyfried; Victoria Prince; Wolfgang Driever Segmentation of the vertebrate hindbrain leads to the formation of a series of rhombomeres with distinct identities. In mouse, Krox20 and kreisler play important...

...Octavian Voiculescu; Emmanuel Taillebourg; Cristina Pujades; Chantal Kress; Stephanie Buart; Patrick Charnay; Sylvie Schneider-Maunoury We have previously demonstrated that inactivation of the Krox20 gene led to the disappearance of its segmental expression territories in the hindbrain...

.... Specific combinations of these markers are associated with each migratory phase in r4, r5 and r6. In Krox20 and kreisler mutant mouse embryos, both of which lack r5, fbm neurones migrate dorsally into the anteriorly positioned r6 and adopt an r6-specific expression pattern. In embryos deficient for Ebf1...

...Faustino Marín; Patrick Charnay ABSTRACT Krox20 and mafB/kr are regulatory genes involved in hindbrain segmentation and anteroposterior (AP) patterning. They are expressed in rhombomeres (r) r3/r5 and r5/r6 respectively, as well as in the r5/r6 neural crest. Since several members of the fibroblast...

... patterning defects were analyzed in embryos individually mutant for Hoxa1 and Hoxa2 in greater detail and extended to embryos mutant for both genes. From these data a model is proposed to describe how Hoxa1, Hoxa2, Hoxb1, Krox20 ( Egr2 ) and kreisler function together to pattern the early mouse hindbrain...

... of activities of Xwnt-8 in Xenopus , and consistent with a role for wnt8 in the specification or patterning of mesoderm. 10 03 1995 © 1995 by Company of Biologists 1995 Danio rerio wnt krox20 gsc pax snail1 spadetail cyclops mesoderm induction pattern formation Injection...