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Keywords: Knock-in
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Journal Articles
Journal: Development
Development (2021) 148 (19): dev199994.
Published: 04 October 2021
... Integrin β1b. Our approach facilitates the generation of knock-in lines in zebrafish, opening the way for accurate quantitative imaging studies. References Ahmed , S. M. , Nishida-Fukuda , H. , Li , Y. , Mcdonald , W. H. , Gradinaru , C. C. and Macara , I. G . ( 2018...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (13): dev197418.
Published: 29 June 2021
...., 2018 ; Mitsui et al., 2003 ; Schrode et al., 2014 ; Strumpf et al., 2005 ). However, we were unable to detect appreciable fluorescent signal in embryos of any of these four mNG2(11) knock-ins in the mNG2(Δ11) background ( Fig. 4 D). We therefore developed a second and alternative knock...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (16): 2810–2821.
Published: 15 August 2015
... leads to normal differentiation of RGCs, whereas replacing Neurod1 by Atoh7 alters the cell fate of amacrine and photoreceptor cells into RGCs ( Mao et al., 2013 , 2008 ), indicating context dependency of gene actions. We knocked Neurog1 into the Atoh1 locus to test whether a bHLH TF...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (19): 3807–3818.
Published: 01 October 2014
... technologies for mouse knockouts and knock-ins ( Capecchi, 2005 ). So far, three different types of nucleases, zinc-finger (ZF) ( Kim et al., 1996 ), transcription activator-like effector (TALE) ( Boch et al., 2009 ; Moscou and Bogdanove, 2009 ) and clustered regularly interspaced short palindromic repeats...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (5): 965–976.
Published: 01 March 2005
... (e-mail: kemler@immunbio.mpg.de ) 22 12 2004 ©2005. 2005 Cell adhesion Knock-in Transcription Gene regulation Gene expression Mouse embryo LCR Comparative genomics E-cadherin-mediated cell-cell adhesion plays an important role in cell sorting, migration and tissue...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (22): 5551–5560.
Published: 15 November 2004
...Richard Chan; W. Rod Hardy; David Dankort; Michael A. Laing; William J. Muller We have generated a series of Erbb2 cDNA knock-in animals to explore the role of signaling pathways coupled to Erbb2 during development. Although this knock-in allele was hypomorphic, expressing tenfold less Erbb2...
Journal Articles
Journal: Development
Development (2003) 130 (8): 1659–1671.
Published: 15 April 2003
... and signal transduction. The β 1 subunit has two isoforms, β 1A ubiquitously expressed and β 1D restricted to striated muscle. They are not functionally equivalent. Replacement of β 1A by β 1D ( β 1D knock-in) in the mouse leads to midgestation lethality on a 50% Ola/50% FVB background [Baudoin, C., Goumans...