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Keywords: Knock in
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Journal Articles
Alexander Hruscha, Peter Krawitz, Alexandra Rechenberg, Verena Heinrich, Jochen Hecht, Christian Haass, Bettina Schmid
Journal:
Development
Development (2013) 140 (24): 4982–4987.
Published: 15 December 2013
... efficient, reaching up to 86.0%, and is heritable. The efficiency of the CRISPR/Cas9 system further facilitated the targeted knock-in of a protein tag provided by a donor oligonucleotide with knock-in efficiencies of 3.5-15.6%. Mutation rates at potential off-target sites are only 1.1-2.5%, demonstrating...
Includes: Supplementary data
