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Keywords: Kidney development
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Journal Articles
Journal: Development
Development (2023) 150 (22): dev201886.
Published: 22 November 2023
... is established during kidney development. More specifically, how signals from the kidney influence vessel maturity and patterning remains poorly understood. Netrin 1 (Ntn1) is a secreted ligand that is crucial for vessel and neuronal guidance. Here, we demonstrate that Ntn1 is expressed by Foxd1 + stromal...
Includes: Supplementary data
Journal Articles
Journal: Development
Series: REVIEW COMMONS TRANSFER
Development (2022) 149 (21): dev201012.
Published: 28 October 2022
...Abhishek Sharma; Marco Meer; Arvydas Dapkunas; Anneliis Ihermann-Hella; Satu Kuure; Seppo J. Vainio; Dagmar Iber; Florence Naillat ABSTRACT Kidneys develop via iterative branching of the ureteric epithelial tree and subsequent nephrogenesis at the branch points. Nephrons form in the cap mesenchyme...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (14): dev200773.
Published: 25 July 2022
... . 10.1002/ajmg.a.38554 Godin , R. E. , Takaesu , N. T. , Robertson , E. J. and Dudley , A. T. ( 1998 ). Regulation of BMP7 expression during kidney development . Development 125 , 3473 - 3482 . 10.1242/dev.125.17.3473 Hartwig , S. , Ho , J. , Pandey , P...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2021) 148 (19): dev199886.
Published: 23 September 2021
... these cells come from as well as their heterogeneity, and reflect on how this information may improve human kidney organoid models. Summary: This Review describes the role of the stroma in mammalian in vivo kidney development and the importance of understanding stromal contributions to induced...
Journal Articles
Journal: Development
Development (2021) 148 (9): dev199386.
Published: 29 April 2021
...Adam Packard; William H. Klein; Frank Costantini ABSTRACT Ret signaling promotes branching morphogenesis during kidney development, but the underlying cellular mechanisms remain unclear. While Ret -expressing progenitor cells proliferate at the ureteric bud tips, some of these cells exit the tips...
Includes: Supplementary data
Journal Articles
Journal Articles
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Journal Articles
Journal: Development
Development (2018) 145 (10): dev153619.
Published: 18 May 2018
... Cheng , H.-T. , Miner , J. H. , Lin , M. , Tansey , M. G. , Roth , K. and Kopan , R. ( 2003 ). Gamma-secretase activity is dispensable for mesenchyme-to-epithelium transition but required for podocyte and proximal tubule formation in developing mouse kidney . Development   130...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (10): dev153619.
Published: 18 May 2018
... Cheng , H.-T. , Miner , J. H. , Lin , M. , Tansey , M. G. , Roth , K. and Kopan , R. ( 2003 ). Gamma-secretase activity is dispensable for mesenchyme-to-epithelium transition but required for podocyte and proximal tubule formation in developing mouse kidney . Development   130...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (24): 4530–4539.
Published: 15 December 2017
.... , Chen , F. , Magella , B. and Potter , S. S. ( 2014 ). Single cell dissection of early kidney development: multilineage priming . Development   141 , 3093 - 3101 . 10.1242/dev.110601 Cheng , H.-T. , Miner , J. H. , Lin , M. , Tansey , M. G. , Roth , K...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (24): 4530–4539.
Published: 15 December 2017
...-licence-1-1/ Summary: Contrary to a previous model, Notch signaling does not promote or repress the formation of a specific nephron segment in mammals. Instead, it promotes nephrogenesis by upregulating Lhx1 and Hnf1b . Notch Nephron segmentation Nephrogenesis Kidney development Wnt4...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2017) 144 (19): 3511–3520.
Published: 1 October 2017
... throughout mammalian kidney development . Cell Stem Cell   3 , 169 - 181 . 10.1016/j.stem.2008.05.020 Li , D. , Mangan , A. , Cicchini , L. , Margolis , B. and Prekeris , R. ( 2014 ). FIP5 phosphorylation during mitosis regulates apical trafficking and lumenogenesis . EMBO...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (15): 2686–2695.
Published: 1 August 2015
... to be required for nephron induction, also instructs the nephron axis such that glomeruli differentiate in regions farthest from the source of Wnt. Kidney development Nephron patterning Glomerulus Mesonephros Chick embryo Wnt signaling The kidney is a vital, bilateral organ that is the central...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (11): 1937–1947.
Published: 1 June 2015
.... Published by The Company of Biologists Ltd 2015 Summary: This review discusses recent advances in the directed differentiation of pluripotent cells into kidney tissues, and how these inform our understanding of human renal development. Kidney development Directed differentiation Mesoderm...
Journal Articles
Journal: Development
Development (2015) 142 (7): 1254–1266.
Published: 1 April 2015
... transcription in NPCs. We confirm that WT1 is required for Gas1 expression in kidneys in vivo . Loss of function of GAS1 in vivo results in hypoplastic kidneys with reduced nephron mass due to premature depletion of NPCs. Although kidney development in Gas1 knockout mice progresses normally until E15.5, NPCs...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (15): 3093–3101.
Published: 1 August 2014
...Eric W. Brunskill; Joo-Seop Park; Eunah Chung; Feng Chen; Bliss Magella; S. Steven Potter We used a single cell RNA-seq strategy to create an atlas of gene expression patterns in the developing kidney. At several stages of kidney development, histologically uniform populations of cells give rise...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (7): 1442–1452.
Published: 1 April 2014
... of Biologists Ltd 2014 Kidney development Nephron progenitor Groucho Odd-skipped Osr1 Six2 Wnt signaling Kidneys play a crucial role in bodily health and homeostasis by filtering metabolic waste and excess fluid from the blood. In mammals, kidney morphogenesis begins...
Includes: Supplementary data