... activity gradient characterize cells in following rows. Depletion of keratin (krt8) with antisense morpholinos results in high traction stresses in follower row cells, misdirected protrusions and the formation of actin stress fibers anchored in streak-like focal adhesions. We propose that maintenance...

... to normal cellular function. We demonstrate here that,in the developing placenta of the mouse, the absence of the Mrj (Dnajb6)co-chaperone prevents proteasome degradation of keratin 18 (K18; Krt18)intermediate filaments, resulting in the formation of keratin inclusion bodies. These inclusions in chorionic...

... 28 9 2004 © 2004. 2004 Pre-placodal ectoderm Neural crest foxD3 zic2 sox2 sox3 keratin dlx5 dlx6 Cell fate determination Patterning Xenopus It was discovered over a century ago that the cranial sensory organs of vertebrates arise from discrete areas...

[email protected] ) 2 1 2002 © 2002. 2002 Permeability barrier Tight junctions Claudins Claudin 6 Mouse Skin Epidermis Keratin Involucrin Filaggrin Small proline rich proteins Kruppel-like factor This work is dedicated to Dr Rosa Beddington for her generosity...

... concentrated in the precursor cells to the hair shaft, where TOPGAL expression was co-induced with hair-specific keratin genes containing LEF/TCF-binding motifs. LEF1 and TOPGAL expression ceased during catagen and telogen, but reappeared at the start of the postnatal hair cycle, concomitant with precortex...

...Alison M. Snape; Robert S. Winning; Thomas D. Sargent This paper identifies a new, developmental role for transcription factor AP-2 in the activation of amphibian embryonic epidermal keratin gene expression. Keratin transcription factor KTF-1 is shown by several criteria to be identical or closely...

... monoclonal antibody LP1K reacts strongly with newt blastemal cells, while its reactivity is restricted in normal limbs. By screening a cDNA expression library from the newt blastema with LP1K, we have identified cDNA clones coding for a type II keratin (NvKH) expressed both in the mesenchyme...

...G. Schaart; C. Viebahn; W. Langmann; F. Ramaekers ABSTRACT The expression of the intermediate filament (IF) constituents desmin, vimentin and keratin, as well as the striated-muscle-specific marker titin, was studied in mouse embryos of 8.0 to 9.5 days post coitum (d.p.c.), using the indirect...

... as epidermis assessed both histologically and by immunofluorescence using an antibody to epidermal keratin. The fate of labelled cells in AP-VP combinations was quite different and confirms the reality of mesoderm induction. In combinations made at stages and 8 the proportion of AP-derived mesoderm...