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Keywords: KIT
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Reproductive biology
Journal: Development
Development (2023) 150 (10): dev201430.
Published: 24 May 2023
.... , De Rooij , D. G. and Van Pelt , A. M. ( 1999 ). Differential expression of c-kit in mouse undifferentiated and differentiating type A spermatogonia . Endocrinology 140 , 5894 - 5900 . 10.1210/endo.140.12.7172 Shami , A. N. , Zheng , X. , Munyoki , S. K. , Ma , Q...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2018) 145 (21): dev166363.
Published: 5 November 2018
... that two ductal progenitor populations, marked exclusively by KRT14 and KIT, maintain non-overlapping ductal compartments after radiation exposure but do so through distinct cellular mechanisms. KRT14 + progenitor cells are fast-cycling cells that proliferate in response to radiation-induced damage...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (19): 3430–3439.
Published: 1 October 2017
... of spermatogonia. MAGE-A4 marks all spermatogonia, KIT marks all B spermatogonia and UCLH1 all Apale-dark (Ap-d) spermatogonia. We suggest that at the start of the spermatogenic lineage there are Ap-d spermatogonia that are GFRA1 High , likely including the spermatogonial stem cells. Next, UTF1 becomes expressed...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2016) 143 (13): 2311–2324.
Published: 1 July 2016
... morphogenesis and differentiation into proacini by suppressing Kit expression through the upregulation of the transcription factor MYB, and concomitantly increasing the expression of distal progenitor markers. In addition, WNT signaling at the early stage of SMG development promoted end bud cell proliferation...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (5): 996–1002.
Published: 1 March 2013
... be divided into establishment of the MSC, recruitment of the MSC to produce committed daughter cells, and the proliferation, differentiation and survival of these daughter cells. Reduction of Kit signaling results in dose-dependent reduction of melanocytes during larval regeneration. Here, we use clonal...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (2): 280–290.
Published: 15 January 2013
... by an undifferentiated spermatogonial population and transition to a differentiating state involves attained expression of the KIT receptor. We found that impaired function of the X chromosome-clustered microRNAs 221 and 222 (miR-221/222) in mouse undifferentiated spermatogonia induces transition from a KIT – to a KIT...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2006) 133 (8): 1495–1505.
Published: 15 April 2006
... heparin. The detailed protocol is available upon request. The antibody detection and colorization was carried out as on sections, using an AP-conjugated anti-DIG antibody and BM purple AP substrate (Roche). Testicular sections of young mice were double stained for Kit or Ngn3 and galectin 1...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2001) 128 (11): 1943–1949.
Published: 1 June 2001
...John F. Rawls; Stephen L. Johnson Embryonic neural crest-derived melanocytes and their precursors express the kit receptor tyrosine kinase and require its function for their migration and survival. However, mutations in kit also cause deficits in melanocytes that make up adult pigment patterns...
Journal Articles
Journal: Development
Development (2000) 127 (17): 3715–3724.
Published: 1 September 2000
... in the regenerating fin and their requirement for the kit receptor tyrosine kinase. Using pre-existing melanin as a lineage tracer, we show that most fin regeneration melanocytes develop from undifferentiated precursors, rather than from differentiated melanocytes. Mutational analysis reveals two distinct classes...
Journal Articles
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (1996) 122 (11): 3597–3605.
Published: 1 November 1996
... transient (B6-Y AKR ) or severe (B6-Y TIR ) XY DOM sex reversal. We report that a point mutation, the dominant white spotting oncogene allele, Kit W-42J , exacerbates XY DOM sex reversal. In B6-Y AKR , penetrance of the trait is low; however, in B6-Y TIR , Kit W-42J exacerbated sex reversal...