...: During tissue closure in Drosophila , Pvr is required for efficient corpse clearance by hemocytes and for protrusive activity in the epidermis. Cell removal Dorsal closure Drosophila Jun kinase PIP3 Pvr Receptor tyrosine kinase Morphometric analysis Thorax closure Tissue closure...

... Dok Jun kinase The synchronized movement of epithelial cell layers is an essential aspect of morphogenesis in the development of many animals(Martin and Wood, 2002). Embryonic dorsal closure (DC), which represents such an epithelial morphogenetic event in Drosophila , begins at stage 11...

..., have planar polarity defects that include achirality, reversed chirality and misrotation. Mutants in the JNK pathway act as dominant suppressors of the hnt planar polarity phenotype, suggesting that HNT functions to downregulate JUN kinase (JNK) signaling during the establishment of ommatidial planar...