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Keywords: Jagged
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Journal Articles
Journal: Development
Development (2022) 149 (7): dev200339.
Published: 7 April 2022
... by Wnt16, directly instruct HSC fate in a shared vascular precursor. However, it remains unclear how this signaling cascade is spatially and temporally regulated within somites. Here, we show in zebrafish that an additional somitic Notch ligand, Jagged 2b (Jag2b), induces intercellular signaling to drive...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (2): 258–267.
Published: 15 January 2015
... Highlighted article : In the adult mouse lung, Notch3 identifies a population of parabasal cells and regulates the balance between basal and parabasal progenitor pools. Notch Basal cells p63 Airway differentiation Progenitor cells Lung regeneration Jagged COPD Basal cells are multipotent...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2011) 138 (17): 3593–3612.
Published: 1 September 2011
... interests. © 2011. Cis-inhibition Delta-like Signaling diversity Jagged Notch Notch intracellular domain Cells need to sense cues from their extracellular environment and integrate this information into appropriate developmental or physiological responses. Although...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (11): 1843–1852.
Published: 1 June 2010
...Elizabeth Zuniga; Frank Stellabotte; J. Gage Crump The development of the vertebrate face relies on the regionalization of neural crest-derived skeletal precursors along the dorsoventral (DV) axis. Here we show that Jagged-Notch signaling ensures dorsal identity within the hyoid and mandibular...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (9): 2203–2213.
Published: 1 May 2005
... by genes like BLADE ON PETIOLE1 ( BOP1 ), which prevent the development of ectopic meristematic activity that leads to the formation of new organs, and JAGGED ( JAG ), which control the proximodistal development of the leaf by regulating cell-division activity. We have isolated and characterized the BOP1...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (22): 5753–5766.
Published: 15 November 2004
...Kristin Lorent; Sang-Yeob Yeo; Takaya Oda; Settara Chandrasekharappa; Ajay Chitnis; Randolph P. Matthews; Michael Pack The Alagille Syndrome (AGS) is a heritable disorder affecting the liver and other organs. Causative dominant mutations in human Jagged 1 have been identified in most AGS patients...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (5): 1101–1110.
Published: 1 March 2004
...José R. Dinneny; Ramin Yadegari; Robert L. Fischer; Martin F. Yanofsky; Detlef Weigel Position-dependent regulation of growth is important for shaping organs in multicellular organisms. We have characterized the role of JAGGED , a gene that encodes a protein with a single C 2 H 2 zinc-finger...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (5): 1111–1122.
Published: 1 March 2004
... at the JAGGED ( JAG ) locus result in Arabidopsis plants with abnormally shaped lateral organs including serrated leaves, narrow floral organs, and petals that contain fewer but more elongate cells. jag mutations also suppress bract formation in leafy,apetala1 and apetala2 mutant backgrounds. The JAG gene...
Journal Articles
Journal: Development
Development (2004) 131 (4): 903–913.
Published: 15 February 2004
... progenitors in vitro. In addition, culturing allowed us to follow cells isolated from the rhombic lip, which is a transient structure that disappears during normal embryogenesis. Rhombic lip Cerebellum Cerebellar granule cells Neurite Notch Delta Jagged Hes Knockout Mouse The highly...