...Lucy Cherbas; Xiao Hu; Igor Zhimulev; Elena Belyaeva; Peter Cherbas The three Drosophila EcR isoforms differ only at their N termini;thus, they share the conserved ligand-binding domain transcriptional activation function (AF2) and only differ in the unconserved A/B region, which contains a second...

... examined the differential expression and function of two Pitx2 isoforms (Pitx2a and Pitx2c) that differ in the region 5′ to the homeodomain, in early chick embryogenesis. Northern blot and RT-PCR analyses indicated the existence of Pitx2a and Pitx2c but not Pitx2b in the developing chick embryos. In situ...

...) asymmetrical pattern formation in body plan. In order to define the genomic structure and roles of Pitx2, we analyzed the genomic structure and generated Pitx2-deficient mice with the lacZ gene in the homeobox-containing exon of Pitx2 . We were able to show that among three isoforms of Pitx2, Pitx2c shows...

... larval salivary gland. A number of these early puffs (2B5, 74EF and 75B) contain complex transcription units (Broad-Complex, E74 and E75 respectively) encoding families of regulatory proteins which are expressed in most if not all tissues. In vitro, transcripts of the different isoforms of these early...

.... We now report a compara-tive analysis of three TGF-β isoforms with respect to gene expression and localization of protein products within the mouse mammary gland. Our studies revealed overlapping expression patterns of TGF- β 1, TGF-β 2 and TGF-β 3 within the epithelium of the actively-growing...

... factor. During oocyte maturation, xnf7 is released into the cytoplasm and is not detectable in nuclei until the mid-blastula-gastrula stage of development. Western blot analysis of xnf7 isolated from oocytes and eggs showed the existence of multiple bands or isoforms of the protein. Unique isoforms...

...Angelika Kaplony; Dieter R. Zimmermann; René W. Fischer; Beata. Imhof; Bernhard F. Odermatt; Kaspar H. Winterhalter; Lloyd Vaughan ABSTRACT The three isoforms of chicken tenascin, an extracellular matrix glycoprotein, are generated by alternatively spliced fibronectin type III domains...

... activities was demonstrated by non-denaturing gel electrophoresis followed by solid-phase enzyme assay. These isoforms were temporally expressed during development, two being correlated with the postnatal reexpression of the ‘embryonic’ form of N-CAM. 14 06 1988 © 1988 by Company of Biologists...