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Keywords: Islets
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Journal Articles
In collection:
Human development
Journal: Development
Development (2018) 145 (16): dev165480.
Published: 15 August 2018
... fetuses. Diabetes Endocrine Human Islets Pancreas Stem cells Because of the limited availability of primary human tissue, much of our knowledge of human organ development is extrapolated from animal models. It is remarkable that the mechanisms of organ formation are conserved enough...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2004) 131 (1): 165–179.
Published: 1 January 2004
... pancreas development:endoderm before pancreas specification, early pancreatic progenitor cells,endocrine progenitor cells and adult islets of Langerhans. These analyses implicate new signaling pathways in endocrine pancreas development, and identified sets of known and novel genes that are temporally...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2003) 130 (20): 4871–4879.
Published: 15 October 2003
... morphogenesis, islet formation and endocrine cell proliferation is impaired in Hhip mutant embryos. Additional loss of one Ptch allele in Hhip –/– Ptch +/– embryos further impairs pancreatic growth and endodermal cell differentiation. These results demonstrate combined requirements for Hhip and Ptch during...