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1-4 of 4
Keywords: Islets
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Journal Articles
In collection:
Human development
Cyrille Ramond, Belin Selcen Beydag-Tasöz, Ajuna Azad, Martijn van de Bunt, Maja Borup Kjær Petersen, Nicola L. Beer, Nicolas Glaser, Claire Berthault, Anna L. Gloyn, Mattias Hansson, Mark I. McCarthy, Christian Honoré, Anne Grapin-Botton, Raphael Scharfmann
Journal:
Development
Development (2018) 145 (16): dev165480.
Published: 15 August 2018
... fetuses. Diabetes Endocrine Human Islets Pancreas Stem cells Because of the limited availability of primary human tissue, much of our knowledge of human organ development is extrapolated from animal models. It is remarkable that the mechanisms of organ formation are conserved enough...
Includes: Supplementary data
Journal Articles
Journal:
Development
Development (2004) 131 (1): 165–179.
Published: 1 January 2004
... pancreas development:endoderm before pancreas specification, early pancreatic progenitor cells,endocrine progenitor cells and adult islets of Langerhans. These analyses implicate new signaling pathways in endocrine pancreas development, and identified sets of known and novel genes that are temporally...
Includes: Supplementary data
Journal Articles
Hiroshi Kawahira, Nancy H. Ma, Emmanouhl S. Tzanakakis, Andrew P. McMahon, Pao-Tien Chuang, Matthias Hebrok
Journal:
Development
Development (2003) 130 (20): 4871–4879.
Published: 15 October 2003
... morphogenesis, islet formation and endocrine cell proliferation is impaired in Hhip mutant embryos. Additional loss of one Ptch allele in Hhip –/– Ptch +/– embryos further impairs pancreatic growth and endodermal cell differentiation. These results demonstrate combined requirements for Hhip and Ptch during...
Journal Articles
Maureen Gannon, Michael K. Ray, Karla Van Zee, Francisco Rausa, Robert H. Costa, Christopher V. E. Wright
Journal:
Development
Development (2000) 127 (13): 2883–2895.
Published: 1 July 2000
... islets. In vivo, HNF6 expression becomes downregulated in pancreatic endocrine cells at 18.5 days post coitum (d.p.c.), when definitive islets first begin to organize. We used an islet-specific regulatory element ( pdx1 PB ) from pancreatic/duodenal homeobox ( pdx1 ) gene to maintain HNF6 expression...