..., they preferentially formed transient cartilage that readily developed into a bony tissue in vivo ( Lee et al., 2018 ). Joint articular cartilage is developed during embryogenesis by a specialized progenitor cell type, named the joint progenitor or interzone cell ( Rux et al., 2019 ), and fetal articular...

...Qin Bian; Yu-Hao Cheng; Jordan P. Wilson; Emily Y. Su; Dong Won Kim; Hong Wang; Sooyeon Yoo; Seth Blackshaw; Patrick Cahan ABSTRACT Synovial joint development begins with the formation of the interzone, a region of condensed mesenchymal cells at the site of the prospective joint. Recently, lineage...

... of combinations of these factors in articular cartilage differentiation. Expression of m Nfia in the developing chick limb skeleton promoted ectopic expression of COL2A1 transcripts in the putative interzone/articular cartilage cells. This is paradoxical considering that embryonic articular cartilage does...

... in the embryonic skeleton. * Authors for correspondence (e-mail: [email protected] ; [email protected] ) 27 4 2008 © 2008. 2008 Chondrogenesis Synovial joints Interzone Gdf5 Chondroitin sulfate Extracellular matrix Mouse embryo Importantly, this genetic loss...