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1-6 of 6
Keywords: Individualization
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Journal Articles
In collection:
Reproductive biology
Lisa Shao, Jaclyn M. Fingerhut, Brook L. Falk, Hong Han, Giovanna Maldonado, Yuemeng Qiao, Vincent Lee, Elizabeth Hall, Liang Chen, Gordon Polevoy, Greco Hernández, Paul Lasko, Julie A. Brill
Journal:
Development
Development (2023) 150 (4): dev200477.
Published: 15 February 2023
... during post-meiotic stages, including a mild defect in spermatid cyst polarization. eIF4E-5 mutants also have a fully penetrant defect in individualization, resulting in failure to produce mature sperm. Indeed, our data indicate that eIF4E-5 regulates non-apoptotic caspase activity during...
Includes: Supplementary data
Journal Articles
In collection:
Reproductive biology
Josefa Steinhauer, Benjamin Statman, Jeremy K. Fagan, Jacob Borck, Satya Surabhi, Prathibha Yarikipati, Daniel Edelman, Andreas Jenny
Journal:
Development
Development (2019) 146 (17): dev179275.
Published: 2 September 2019
... and individualize into mature sperm, each tightly enclosed by a plasma membrane. In Drosophila melanogaster , individualization of sister spermatids requires the formation of specialized actin cones that synchronously move along the sperm tails, removing inter-spermatid bridges and most of the cytoplasm. Here, we...
Includes: Supplementary data
Journal Articles
Journal:
Development
Development (2010) 137 (22): 3775–3784.
Published: 15 November 2010
... processes remain elusive. Here, we report the in vivo analysis of OSBP function in the model organism Drosophila. Osbp mutants are male-sterile and exhibit defects in individualization, the process by which each spermatid is packaged into its own membrane. Overexpression of OSBP leads to post-eclosion...
Includes: Supplementary data
Journal Articles
Journal:
Development
Development (2007) 134 (19): 3517–3525.
Published: 1 October 2007
... subunit is expressed in early stages of spermatogenesis, gradually fading away following meiosis, the testis-specific Prosα6T becomes prominent in spermatid nuclei and cytoplasm after meiosis, and persists in mature sperm. In addition, these subunits are found in numerous `speckles' near individualization...
Journal Articles
Journal:
Development
Development (2003) 130 (9): 1805–1816.
Published: 1 May 2003
...Tatsuhiko Noguchi; Kathryn G. Miller In order to better understand the mechanism of sperm individualization during spermatogenesis in Drosophila melanogaster , we have developed an in vitro culture system in which we can perform live observation of individualization in isolated cysts. The whole...
Includes: Multimedia, Supplementary data
Journal Articles
Journal:
Development
Development (1998) 125 (10): 1833–1843.
Published: 15 May 1998
... in sperm maturation therefore requires the physical resolution of the syncytium, or cyst, into individual cells, a process sometimes referred to as sperm individualization. Despite the identification of specialized machinery involved in the individualization of Drosophila spermatids (Tokuyasu, K. T...