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Keywords: Individualization
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Journal Articles
In collection:
Reproductive biology
Journal: Development
Development (2023) 150 (4): dev200477.
Published: 15 February 2023
... during post-meiotic stages, including a mild defect in spermatid cyst polarization. eIF4E-5 mutants also have a fully penetrant defect in individualization, resulting in failure to produce mature sperm. Indeed, our data indicate that eIF4E-5 regulates non-apoptotic caspase activity during...
Includes: Supplementary data
Journal Articles
In collection:
Reproductive biology
Journal: Development
Development (2019) 146 (17): dev179275.
Published: 2 September 2019
... and individualize into mature sperm, each tightly enclosed by a plasma membrane. In Drosophila melanogaster , individualization of sister spermatids requires the formation of specialized actin cones that synchronously move along the sperm tails, removing inter-spermatid bridges and most of the cytoplasm. Here, we...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (22): 3775–3784.
Published: 15 November 2010
... processes remain elusive. Here, we report the in vivo analysis of OSBP function in the model organism Drosophila. Osbp mutants are male-sterile and exhibit defects in individualization, the process by which each spermatid is packaged into its own membrane. Overexpression of OSBP leads to post-eclosion...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2003) 130 (9): 1805–1816.
Published: 1 May 2003
...Tatsuhiko Noguchi; Kathryn G. Miller In order to better understand the mechanism of sperm individualization during spermatogenesis in Drosophila melanogaster , we have developed an in vitro culture system in which we can perform live observation of individualization in isolated cysts. The whole...
Includes: Multimedia, Supplementary data
Journal Articles
Journal: Development
Development (1998) 125 (10): 1833–1843.
Published: 15 May 1998
... in sperm maturation therefore requires the physical resolution of the syncytium, or cyst, into individual cells, a process sometimes referred to as sperm individualization. Despite the identification of specialized machinery involved in the individualization of Drosophila spermatids (Tokuyasu, K. T...