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Keywords: Imprinted X inactivation
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Journal Articles

Choice of random rather than imprinted X inactivation in female embryonic stem cell-derived extra-embryonic cells

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Kazuhiro Murakami, Kimi Araki, Satoshi Ohtsuka, Teruhiko Wakayama, Hitoshi Niwa
Journal: Development
Development (2011) 138 (2): 197–202.
https://doi.org/10.1242/dev.056606
Published: 15 January 2011
.... Embryonic stem cells Extra-embryonic lineages Imprinted X inactivation Mouse In eutherian mammals, female cells have two X chromosomes, derived from oocyte and sperm. In adult females, one of the two X chromosomes is inactivated for gene dosage compensation in almost all cell types...
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Includes: Supplementary data