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Journal Articles

The Drosophila caspase Ice is important for many apoptotic cell deaths and for spermatid individualization, a nonapoptotic process

Israel Muro, Deborah L. Berry, Jun R. Huh, Chun Hong Chen, Haixia Huang, Soon Ji Yoo, Ming Guo, Eric H. Baehrecke, Bruce A. Hay
Journal: Development
Development (2006) 133 (17): 3305–3315.
https://doi.org/10.1242/dev.02495
Published: 1 September 2006
... and amplify these signals by cleaving and thereby activating effector caspases. In Drosophila , the initiator caspase Nc(previously Dronc) cleaves and activates two short-prodomain caspases, Dcp-1 and Ice (previously Drice), suggesting these as candidate effectors of Nc killing activity. dcp-1 -null mutants...
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Includes: Supplementary data