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Keywords: IRF6
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Journal Articles

An Irf6 - Esrp1/2 regulatory axis controls midface morphogenesis in vertebrates

Shannon H. Carroll, Claudio Macias Trevino, Edward B. Li, Kenta Kawasaki, Nikita Myers, Shawn A. Hallett, Nora Alhazmi, Justin Cotney, Russ P. Carstens, Eric C. Liao
Journal: Development
Development (2020) 147 (24): dev194498.
https://doi.org/10.1242/dev.194498
Published: 23 December 2020
...Shannon H. Carroll; Claudio Macias Trevino; Edward B. Li; Kenta Kawasaki; Nikita Myers; Shawn A. Hallett; Nora Alhazmi; Justin Cotney; Russ P. Carstens; Eric C. Liao ABSTRACT Irf6 and Esrp1 are important for palate development across vertebrates. In zebrafish, we found that irf6 regulates...
View article titled, An <span class="search-highlight">Irf6</span> - Esrp1&#x2F;2 regulatory axis controls midface morphogenesis in vertebrates
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Includes: Supplementary data
Journal Articles

Smad4 - Irf6 genetic interaction and TGFβ-mediated IRF6 signaling cascade are crucial for palatal fusion in mice

Jun-ichi Iwata, Akiko Suzuki, Richard C. Pelikan, Thach-Vu Ho, Pedro A. Sanchez-Lara, Mark Urata, Michael J. Dixon, Yang Chai
Journal: Development
Development (2013) 140 (6): 1220–1230.
https://doi.org/10.1242/dev.089615
Published: 15 March 2013
... transforming growth factor beta (TGFβ) signaling molecules and interferon regulatory factor 6 (Irf6) have been identified as genetic risk factors for cleft palate, little is known about the relationship between TGFβ signaling and IRF6 activity during palate formation. Here, we show that TGFβ signaling...
View article titled, Smad4 - <span class="search-highlight">Irf6</span> genetic interaction and TGFβ-mediated <span class="search-highlight">IRF6</span> signaling cascade are crucial for palatal fusion in mice
Open the PDF for Smad4 - <span class="search-highlight">Irf6</span> genetic interaction and TGFβ-mediated <span class="search-highlight">IRF6</span> signaling cascade are crucial for palatal fusion in mice in another window
Includes: Supplementary data
Journal Articles

Distinct requirements for wnt9a and irf6 in extension and integration mechanisms during zebrafish palate morphogenesis

Max Dougherty, George Kamel, Michael Grimaldi, Lisa Gfrerer, Valeriy Shubinets, Renee Ethier, Graham Hickey, Robert A. Cornell, Eric C. Liao
Journal: Development
Development (2013) 140 (1): 76–81.
https://doi.org/10.1242/dev.080473
Published: 1 January 2013
... for palatal extension, wherein the chondrocytes form a proliferative front, undergo morphological change and intercalate to form the ethmoid plate. Meanwhile, irf6 is required specifically for integration of facial prominences along a V-shaped seam. This work presents a mechanistic analysis of palate...
View article titled, Distinct requirements for wnt9a and <span class="search-highlight">irf6</span> in extension and integration mechanisms during zebrafish palate morphogenesis
Open the PDF for Distinct requirements for wnt9a and <span class="search-highlight">irf6</span> in extension and integration mechanisms during zebrafish palate morphogenesis in another window
Includes: Multimedia, Supplementary data