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Keywords: Hypoblast
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Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (2013) 140 (5): 965–975.
Published: 1 March 2013
... and WWTR1 showed mutually distinct localisation patterns that suggest non-redundant roles. NANOG and GATA6 were conserved as markers of epiblast and hypoblast, respectively, but some differences to the mouse were found in their mode of differentiation. Our results suggest that there is considerable...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2009) 136 (19): 3215–3222.
Published: 1 October 2009
... but suppresses development of the hypoblast. The size of the inner cell mass(ICM) compartment is not reduced, however. Throughout the ICM, the epiblast-specific marker Nanog is expressed, and in XX embryos epigenetic silencing of the paternal X chromosome is erased. Epiblast identity and pluripotency were...
Journal Articles
Journal: Development
Development (2003) 130 (15): 3491–3501.
Published: 1 August 2003
... between the hypoblast and the definitive endoderm was defined by following labeled rostral primitive-streak cells over a short period of time as they contributed to the definitive endoderm, and combining this with in situ hybridization with a riboprobe for Crescent , a marker of the hypoblast. We show...
Journal Articles
Journal: Development
Development (2000) 127 (17): 3839–3854.
Published: 1 September 2000
... recently. In the mouse, the finding that the visceral endoderm (VE) is required for forebrain development has been interpreted as support for the latter model. Here we argue that the chick hypoblast is equivalent to the mouse VE, based on fate, expression of molecular markers and characteristic anterior...
Journal Articles
Journal Articles
Journal: Development
Development (1997) 124 (13): 2561–2570.
Published: 1 July 1997
... with a timing that corresponded to onset of cardiac myocyte differentiation in vivo. Isolation and recombination experiments demonstrated that a signal from the hypoblast was required to induce cardiac myogenesis in the epiblast, and regional differences in epiblast responsiveness and hypoblast inductiveness...
Journal Articles
Journal: Development
Development (1994) 120 (12): 3571–3579.
Published: 1 December 1994
... (with or without hypoblast tissue) were able to form Hb, whereas inner-core pieces from the pre-hypoblast stages, namely stages X and XI, did not form Hb. The capacity to form Hb, however, could be conferred upon the inner-core pieces from stage X epiblasts if bFGF at a concentration of 75-150 ng/ml was added...
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (1991) 112 (2): 431–438.
Published: 1 June 1991
... % and 60 % epiboly, we observed a ring-shaped group of labeled cells, which probably have involuted during early gastrulation. Consequently, this cell group may correlate with the leading edge of the hypoblast layer within the germ ring. At 60 % epiboly and later, the blastodermal cells are dye-uncoupled...
Journal Articles
Journal: Development
Development (1990) 109 (3): 667–682.
Published: 1 July 1990
...Claudio D. Stern ABSTRACT The marginal zone of the chick embryo has been shown to play an important role in the formation of the hypoblast and of the primitive streak. In this study, time-lapse filming, fate mapping, ablation and trans plantation experiments were combined to study its contribution...
Journal Articles
Journal: Development
Development (1988) 104 (4): 643–655.
Published: 1 December 1988
...David R. Canning; Claudio D. Stern We report that a monoclonal antibody, HNK-1, identifies specific regions and cell types during primitive streak formation in the chick blastoderm. Immunohistochemical studies show that the cells of the forming hypoblast are HNK-1 positive from the earliest time...
Journal Articles
Journal: Development
Development (1985) 89 (1): 235–241.
Published: 1 October 1985
... competent to develop any sort of axial structures nor has the capacity to generate an inductive layer. 15 04 1985 Copyright © 1985 by Company of Biologists 1985 induction marginal zone totipotency hypoblast chick embryo At stage X( Eyal-Giladi & Kochav, 1976 ) the chick...