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1-2 of 2
Keywords: Hyperpolarization
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Journal Articles
Journal:
Development
Development (2008) 135 (5): 859–867.
Published: 1 March 2008
... causes a negative shift (hyperpolarization) of the resting potential of myoblasts. After exploring various mechanisms, we found that this upregulation of Kir2.1 was due to dephosphorylation of the channel itself. Application of genistein,a tyrosine kinase inhibitor, increased Kir2.1 activity...
Journal Articles
Journal:
Development
Development (2006) 133 (16): 3107–3114.
Published: 15 August 2006
...Stéphane Konig; Anne Béguet; Charles R. Bader; Laurent Bernheim In human myoblasts triggered to differentiate, a hyperpolarization,resulting from K + channel (Kir2.1) activation, allows the generation of an intracellular Ca 2+ signal. This signal induces an increase in expression/activity of two...