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Keywords: Huntington's disease
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Journal Articles
Journal: Development
Development (2021) 148 (19): dev199513.
Published: 5 October 2021
...Szilvia Galgoczi; Albert Ruzo; Christian Markopoulos; Anna Yoney; Tien Phan-Everson; Shu Li; Tomomi Haremaki; Jakob J. Metzger; Fred Etoc; Ali H. Brivanlou ABSTRACT Huntington's disease (HD) is a fatal neurodegenerative disorder caused by an expansion of the CAG repeats in the huntingtin gene ( HTT...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (2015) 142 (7): 1375–1386.
Published: 1 April 2015
... (hESCs) and induced pluripotent stem cells (hiPSCs) is fundamental for realising their promise in disease modelling, pharmaceutical drug screening and cell therapy for Huntington's disease. GABAergic medium-sized spiny neurons (MSNs) are the principal projection neurons of the striatum and specifically...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
Journal: Development
Development (1990) 108 (Supplement): 107–113.
Published: 1 April 1990
... of affected traits. Copyright © 1990 by Company of Biologists 1990 sex-linked modifying loci dosage-sensitive modifiers Drosophila variegation Huntington’s disease Genome imprinting may be operationally defined as the process that results in the gamete-of-origin-dependent modification...