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Keywords: Human embryonic stem cell
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Journal Articles
Journal Articles
Journal: Development
Development (2015) 142 (18): 3198–3209.
Published: 15 September 2015
.../nodal, BMPs and Wnt/β-catenin that define anterior-posterior patterning and specify downstream derivatives including cardiomyocyte, endothelial and hematopoietic cells. We used human embryonic stem cells to explore how these pathways control mesodermal fate choices in vitro. Varying doses of activin...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (18): 3799–3808.
Published: 15 September 2013
... suppression of Wnt/β-catenin signaling, but the mechanism for this is not well understood. By analyzing gene expression and chromatin dynamics during directed differentiation of human embryonic stem cells (hESCs), we identified a suppressor of Wnt/β-catenin signaling, transmembrane protein 88 (TMEM88...
Includes: Supplementary data
Journal Articles