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Keywords: Human development
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Journal Articles
Journal: Development
Development (2022) 149 (13): dev200171.
Published: 6 July 2022
...-gestation determines the in vivo counterpart of in vitro trophoblast cultures and identifies key regulators of human trophoblast stem cell self renewal. Human development Human trophoblast stem cells Placenta development Self-renewal Trophoblast Wellcome Trust http://dx.doi.org...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal: Development
Development (2020) 147 (12): dev187344.
Published: 26 June 2020
... muscle development in vitro using scRNA-seq of a FACS-sorted PAX7-YFP iPSC reporter line shows the developmental stages of the PAX7 + precursors and their myogenic potential. PAX7 Skeletal muscle Human development Pluripotent stem cell Satellite cell Adult skeletal muscles...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (8): dev166173.
Published: 16 April 2019
... intestine. Future studies can employ similar technical approaches using different microbial strains to broaden our understanding of microbiome interactions during early human development. Notably, efforts have defined conditions in which 3D epithelial-only gastric and intestinal organoids can be plated...
Journal Articles
In collection:
Human development
Journal: Development
Development (2018) 145 (17): dev163550.
Published: 16 August 2018
... understanding of endoderm development. Endoderm Organoids Human development Keystone Many internal organ systems of the body, including the lungs, liver, gastrointestinal tract and pancreas, as well as the often forgotten thyroid, prostate, bladder and tongue, are all derived from the germ...
Journal Articles
Journal: Development
Development (2018) 145 (16): dev150433.
Published: 23 July 2018
... prompt further consideration of the somatic cell fate decisions that occur during early human development. Understanding the specification and origin of PGCs, in addition to that of the three somatic lineages that occur in gastrulating human embryos, is pivotal for advances in regenerative medicine...
Journal Articles
Journal: Development
Development (2017) 144 (14): 2544–2547.
Published: 15 July 2017
... of xenogeneic barriers and mechanisms of heterochronicity, to modeling human development, and to the creation of human transplantable organs. A concern in the context of human-animal chimera generation is the possibility of producing human gametes. If spermatozoa or eggs were to be formed in interspecies...
Journal Articles
Journal: Development
Development (2017) 144 (12): 2099–2103.
Published: 15 June 2017
... are now in the era of human developmental biology. In this review of the recent RIKEN Center for Developmental Biology (CDB) symposium ʻTowards Understanding Human Development, Heredity, and Evolution' ( Fig. 1 ), we summarize some of the prominent talks and take-home messages from the symposium...
Journal Articles
Journal: Development
Development (2017) 144 (9): 1584–1587.
Published: 1 May 2017
... models of human development and disease. Together, these technologies will move past characterization to the prediction of human developmental and disease-related phenomena. * Author for correspondence ( barbara_treutlein@eva.mpg.de ) Competing interests The authors declare no competing...
Journal Articles
Journal: Development
Development (2017) 144 (6): 958–962.
Published: 15 March 2017
... organoids are now being used as a primary research tool to investigate human developmental biology. * Author for correspondence ( james.wells@cchmc.org ) Competing interests The authors declare no competing or financial interests. © 2017. Published by The Company of Biologists Ltd 2017...
Includes: Supplementary data
Journal Articles
In collection:
Neural development
Journal: Development
Development (2016) 143 (21): 3969–3981.
Published: 1 November 2016
.... Published by The Company of Biologists Ltd 2016 http://www.biologists.com/user-licence-1-1/ Highlighted article: Tissue-clearing and imaging of intact human embryos reveals previously unprecedented GnRH neuron target sites and routes of migration into the brain. GnRH neurons Human...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (18): 3073–3076.
Published: 15 September 2015
... the remit and efforts of the Human Developmental Biology Resource – and other similar projects – that provides researchers with access to human tissue and related services. Bioinformatics portals Congenital anomalies Gene expression Human development Human embryo Tissue bank Introduction...
Journal Articles
Journal: Development
Development (2015) 142 (1): 17–20.
Published: 1 January 2015
...Alexander Medvinsky; Frederick J. Livesey In September 2014, over 100 scientists from around the globe gathered at Wotton House near London for the Company of Biologists' workshop ‘From Stem Cells to Human Development’. The workshop covered diverse aspects of human development, from the earliest...
Journal Articles
Journal: Development
Development (1990) 108 (Supplement): 115–123.
Published: 1 April 1990
... and retinoblastoma genes in human development H. GHAZI, A. N. MAGEWU, F. GONZALES and P. A. JONES Department of Biochemistry and Kenneth Norris Jr Comprehensive Cancer Center, University of Southern California Medical School. Los Angeles, California 90033, USA Summary The methylation status of the c-H-ras-1, insulin...