... published data and immunofluorescence analysis for candidate genes, we present a basic blueprint for human hypoblast differentiation, lending support to the proposed model of sequential segregation of the founder lineages of the human blastocyst. The first characterised marker, specific initially...

... human blastocyst inner cell mass trophectoderm human IVF Despite the diversity of eutherian mammals, their early development is very similar (Wimsatt, 1975). Following fertilization, the zygote, enclosed in an acellular envelope, the zona pellucida, undergoes a number of cleavage divisions...