...-giessen.de ) Competing interests statement The authors declare no competing financial interests. © 2012. Igf2/H19 Cohesin Homeotic gene Imprint Insulator As early as the 1950s, the existence of genomic insulators has been postulated based on several observations...

... for AP3 and those obtained for its Antirrhinum ortholog DEF suggest that the mechanisms by which these Arabidopsis and Antirrhinum floral homeotic genes act to specify organ identity have diverged during the evolution of these species. We have developed a new strategy, based...

... Artemia -like pattern of homeotic gene expression has apparently been modified in the insect lineage associated with and perhaps facilitating the observed pattern of tagmatization. Since insects are the only arthropods with a derived trunk tagmosis tested to date, we examined the expression patterns...

... Homeotic gene Transcriptional regulation Floral organ development in Arabidopsis is regulated by three classes of floral organ identity genes. Each class of organ identity genes is expressed in two adjacent regions of four concentric whorls of flower buds (the ABC model; Bowman et al., 1991...

... and L3 contribute, to different degrees, to the mesophyll and other internal tissues. In order to test the roles of the floral homeotic genes in regulating these patterns of cell proliferation, we carried out similar clonal analyses in apetala3-3 and agamous-1 mutant plants. Our results suggest that cell...

... 1999 © 1999 by Company of Biologists 1999 Arnt Aryl hydrocarbon receptor Dioxin receptor Drosophila homeotic gene PAS domain Antennal specification Limb development spineless-aristapedia tango Loss-of-function mutations in the Drosophila spineless ( ss ) gene...

...Arhat Abzhanov; Thomas C. Kaufman ABSTRACT Homeotic genes are known to be involved in patterning morphological structures along the antero-posterior axis of insects and vertebrates. Because of their important roles in development, changes in the function and expression patterns of homeotic genes...

...Frank Hirth; Beate Hartmann; Heinrich Reichert ABSTRACT Studies in vertebrates show that homeotic genes are involved in axial patterning and in specifying segmental identity of the embryonic hindbrain and spinal cord. To gain further insights into homeotic gene action during CNS development, we...

... ). Homeotic genes and the evolution of the arthropods and chordates . Nature 376 , 479 – 485 . 10.1038/376479a0 Casares , F. , Calleja , M. and Sanchez-Herrero , E. ( 1996 ). Functional similarity in appendage specifcation by the Ultrabithorax and abdominal-A Drosophila HOX genes...

... 1997 extradenticle Drosophila development homeotic gene midgut development Fig. 2. EXD is cytoplasmic throughout cellular blastoderm (stage 5) embryos. Wild-type embryo, double labelled with DAPI (red) and anti-EXD (green). In both the monolayer of somatic cells and the germ...

...Josef G. Heuer; Kaijun Li; Thomas C. Kaufman ABSTRACT The products of the homeotic genes in Drosophila are transcription factors that are necessary to impose regional identity along the anterior-posterior axis of the developing embryo. However, the target genes under homeotic regulation...

...Anne Chiang; Michael B. O’Connor; Renato Paro; Jeff Simon; Welcome Bender ABSTRACT The Polycomb protein of Drosophila melanogaster maintains the segmental expression limits of the homeotic genes in the bithorax complex. Polycomb-binding sites within the bithorax complex were mapped...

... cephalic segments. In the mandibular segment, cnc has a classical homeotic effect: mandibular structures are missing in cnc mutant larvae and replaced with duplicate maxillary structures. We propose that cnc functions in combination with the homeotic gene Deformed to specify mandibular development. Labral...

..., USA 18 03 1994 © 1994 by Company of Biologists 1994 homeobox homeotic gene fushi tarazu short germ insect grasshopper locust Among the arthropods, homeotic genes of the Antennapedia (Antp) class are generally well conserved. Homeobox exons of these genes have been...

...Michael Akam; Michalis Averof; James Castelli-Gair; Rachel Dawes; Francesco Falciani; David Ferrier ABSTRACT Comparisons between Hox genes in different arthropods suggest that the diversity of Antennapedia-class homeotic genes present in modern insects had already arisen before the divergence...

...Kenneth D. Irvine; Juan Botas; Sanjaya Jha; Richard S. Mann; David S. Hogness ABSTRACT The Drosophila homeotic gene Ultrabithorax ( Ubx ) encodes transcriptional regulatory proteins (UBX) that specify thoracic and abdominal segmental identities. Ubx autoregulation was examined by manipulating UBX...

...Robert Kelsh; Iain Dawson; Michael Akam ABSTRACT We have cloned a homologue of the homeotic gene Abdominal-B from the locust Schistocerca gregaria and raised antibodies against the homeodomain and C-terminal flanking region of the encoded protein. This antibody stains the posterior abdomen...

...Alex P. Gould; Robert A. H. White ABSTRACT The homeotic genes of Drosophila encode transcription factors that specify morphological differences between segments. To identify the genes that they control, we developed a chromatin immunopurification approach designed to isolate in vivo binding sites...

...Gabi Tremml; Mariann Bienz ABSTRACT Extracellular signal proteins induce the homeotic gene labial ( lab ) to high levels of localised expression in the endoderm of Drosophila embryos. We aimed to identify cis -regulatory elements within the lab gene that respond to this induction by analysing...

...Kohji Ueno; Chi-Chung Hui; Masakazu Fukuta; Yoshiaki Suzuki ABSTRACT The E loci in Bombyx mori are expected to contain a homeotic gene complex specifying the identities of the larval abdominal segments. However, the molecular structure of this complex remains to be determined. We have started...