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Keywords: Homeostasis
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Journal Articles
Journal: Development
Development (2022) 149 (8): dev199903.
Published: 3 May 2022
... against germs. New and exciting interactions, such as crosstalk between stem cells and immune cells, are being explored. Such interactions are observed in the development, homeostasis, or post-inflammatory regeneration of tissues across evolution. Here, we describe the evolution of adaptive immune-like...
Journal Articles
Journal: Development
Development (2020) 147 (22): dev194100.
Published: 15 November 2020
...Pooja Flora; Elena Ezhkova ABSTRACT Cell divisions and cell-fate decisions require stringent regulation for proper tissue development and homeostasis. The mammalian epidermis is a highly organized tissue structure that is sustained by epidermal stem cells (ESCs) that balance self-renewal and cell...
Journal Articles
Journal: Development
Development (2020) 147 (10): dev186312.
Published: 21 May 2020
.../ Highlighted Article: An optimized approach to developmental arrest of third instar Drosophila larvae offers new insights into the mechanisms of synaptic growth, function, homeostatic plasticity and neurodegeneration at a model glutamatergic synapse. Homeostasis Synapse Neurotransmission...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (23): dev177790.
Published: 2 December 2019
...Ludmila Gordon; Janna Blechman; Eyal Shimoni; Dvir Gur; Bela Anand-Apte; Gil Levkowitz ABSTRACT To maintain body homeostasis, endocrine systems must detect and integrate blood-borne peripheral signals. This is mediated by fenestrae, specialized permeable pores in the endothelial membrane...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (9): dev156000.
Published: 2 May 2019
...Marine Theret; Remi Mounier; Fabio Rossi ABSTRACT The discovery of new non-canonical (i.e. non-innate immune) functions of macrophages has been a recurring theme over the past 20 years. Indeed, it has emerged that macrophages can influence the development, homeostasis, maintenance and regeneration...
Journal Articles
In collection:
Human development
Journal: Development
Development (2017) 144 (16): 2862–2872.
Published: 15 August 2017
...Nicholas D. Hastie ABSTRACT The study of genes mutated in human disease often leads to new insights into biology as well as disease mechanisms. One such gene is Wilms’ tumour 1 ( WT1 ), which plays multiple roles in development, tissue homeostasis and disease. In this Primer, I summarise how...
Journal Articles
Journal: Development
Development (2016) 143 (20): 3639–3649.
Published: 15 October 2016
...Joep Beumer; Hans Clevers The intestinal epithelium is the fastest renewing tissue in mammals and has a large flexibility to adapt to different types of damage. Lgr5 + crypt base columnar (CBC) cells act as stem cells during homeostasis and are essential during regeneration. Upon perturbation...
Journal Articles
Journal: Development
Development (2016) 143 (19): 3532–3539.
Published: 1 October 2016
...Yutaka Takada; Akihisa Fukuda; Tsutomu Chiba; Hiroshi Seno Brg1, a core subunit of the SWI/SNF chromatin remodeling complex, is essential for development and homeostasis of various organs. However, the functional role of Brg1 in intestinal development and homeostasis, and the underlying molecular...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (5): 764–773.
Published: 1 March 2016
..., normal density is restored. Taken together, these results reveal crucial roles for both BMP signaling and cell shedding in homeostasis of the respiratory epithelium. Fig. 1 shows the results of a screen using small compounds that are either agonists or antagonists for specific intercellular signaling...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2014) 141 (18): 3445–3457.
Published: 15 September 2014
... quiescent stem cell populations, but the exact roles that HH signaling plays in adult organ homeostasis and regeneration remain poorly understood. Here, we review recently identified functions of HH in modulating the behavior of tissue-specific adult stem and progenitor cells during homeostasis...
Journal Articles
Journal: Development
Development (2013) 140 (22): 4522–4532.
Published: 15 November 2013
... Homeostasis Mouse The adrenal capsule is histologically characterized as arising from cells of the intermediate mesoderm. After separation of the individual adrenal primordia (AP, fetal adrenal gland) and gonadal primordial (GP) from the shared adrenogonadal primordia (AGP), mesenchymal cells...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (12): 2548–2561.
Published: 15 June 2013
.... , Simon A. ( 2011 ). Dopamine controls neurogenesis in the adult salamander midbrain in homeostasis and during regeneration of dopamine neurons . Cell Stem Cell 8 , 426 - 433 . Björklund A. , Lindvall O. ( 1975 ). Dopamine in dendrites of substantia nigra neurons: suggestions...
Journal Articles
Journal: Development
Development (2008) 135 (18): 3063–3070.
Published: 15 September 2008
... animals, removed from possible aggressive interactions with other fish, also displayed progressive loss of fin structures (data not shown). Furthermore, similar tissue loss also occurred in dorsal, anal, pelvic and pectoral fins, indicating that Fgf signaling is required for homeostasis in all fin types...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2007) 134 (18): 3383–3392.
Published: 15 September 2007
... and stabilized by CSN-5. We propose the `good cop: bad cop' team of CSN-5 and KGB-1 imposes a balance on GLH-1 levels, resulting in germline homeostasis. In addition, both KGB-1 and CSN-5 bind Vasa, a Drosophila germ granule component; therefore, similar regulatory mechanisms might be conserved from worms...
Includes: Supplementary data