...: BET-family epigenetic readers are essential regulators of the developmental potential of both pluripotent blastula and neural crest cells. Bromodomain Brd4 Histone Acetylation Pluripotency Stem cell Xenopus Neural crest National Institutes of Health http://dx.doi.org/10.13039...

... a chorioallantois fusion defect with early developmental arrest, and the remaining 50% a paucity of epicardium cells (Yang et al., 1995). In addition, Itga4 −/− display defects in coronary vessel network development (Yang et al., 1995), like Ing4 +/− Ing5 −/− embryos. Appropriate histone acetylation...

.... , Dubinsky , M. K. , Ho , J. J. D. , El-Rass , S. , Wang , Y.-D. , Wen , X.-Y. and Marsden , P. A. (2018). Histone acetyltransferase 7 (KAT7)-dependent intragenic histone acetylation regulates endothelial cell gene regulation . J. Biol. Chem. 293 , 4381 - 4402 . 10.1074...

... on a mixed background (100%). Moreover, Dlx5 gene expression was strongly affected by the absence of MOZ (Fig. 2 B,F). To determine whether the Dlx5 gene was likely to be a direct MOZ target, we examined MOZ occupancy and histone acetylation by chromatin immunoprecipitation (ChIP) followed by qPCR...

... characterized by low levels of histone acetylation, and show that increasing HDAC1 levels enhance the ability of blastula cells to be reprogrammed to a neural crest state. Together, these findings elucidate a previously uncharacterized role for HDAC activity in establishing the neural crest stem cell state...

... for the proliferative potential of stem cells in stratified epithelia . Cell   129 , 523 - 536 . 10.1016/j.cell.2007.02.045 Seo , S.-B. , Mcnamara , P. , Heo , S. , Turner , A. , Lane , W. S. and Chakravarti , D. (2001). Regulation of histone acetylation and transcription by INHAT...

...-immunoprecipitates with multiple components of the PAF1 and histone deacetylase-containing NCoR complexes and is not solely required for major histone lysine methylation marks. In the absence of Setd5 , histone acetylation is increased at transcription start sites and near downstream regions. These findings suggest...

... segregation Histone methylation Histone acetylation The fundamental unit of chromatin is the nucleosome, which is composed of two copies each of histones H2A, H2B, H3 and H4. The linker histone H1 lies adjacent to the nucleosomes and facilitates chromosome condensation to establish higher order...

... by The Company of Biologists Ltd 2012 DNA replication Histone acetylation Gene amplification A central unanswered question in DNA replication is the mechanism by which multicellular eukaryotes select sites in their genome to act as origins (Mechali, 2010). A strict DNA consensus for origins has...

.... Finally, NSC plasticity involves specific chromatin modifications. The endogenous glial cells, as well as those induced by Gcm overexpression display low levels of histone 3 lysine 9 acetylation (H3K9ac) and Drosophila CREB-binding protein (dCBP) Histone Acetyl-Transferase (HAT). Moreover, we show...

...-Oriented Science and Technology, Kinki University, Wakayama 649-6493, Japan. 23 9 2008 © 2008. 2008 Nuclear transfer Chromatin remodeling Histone acetylation Histone methylation Oocyte cytoplasm The success of somatic cell cloning gives hope to programs such as species...

... chromatin histone H4 histone acetylation Following fertilization, early development is directed by maternally inherited mRNAs and proteins. The zygotic genome becomes transcriptionally active at a time that is species-dependent (Telford et al., 1990), after which the embryo synthesizes new...