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Keywords: Hindgut
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Journal Articles
Journal: Development
Development (2021) 148 (22): dev199825.
Published: 26 November 2021
... migration can lead to Hirschsprung disease, which is characterized by an aganglionic distal bowel. During the craniocaudal migration of ENCCs along the gut, we find that their proliferation is greatest as the ENCC wavefront passes through the ceca, a pair of pouches at the midgut-hindgut junction in avian...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2020) 147 (8): dev185108.
Published: 12 April 2020
... during embryogenesis. The development of the colon starts with the formation and extension of the hindgut. We show that Wnt3a is expressed in the caudal embryo in a dorsal-ventral (DV) gradient across all three germ layers, including the hindgut. Using genetic and lineage-tracing approaches, we describe...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (22): 4091–4102.
Published: 15 November 2017
... organ-boundary intestinal stem cells (OB-ISCs) is regulated by the neighboring hindgut, a developmentally distinct organ. This distinct OB-ISC control occurs through proximity to a specialized transition zone between the endodermal midgut and ectodermal hindgut that shares molecular signatures of both...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2017) 144 (7): 1283–1295.
Published: 01 April 2017
... in the genome is poorly understood. Here we identified the transcriptomes of Xenopus foregut and hindgut progenitors, which are conserved with mammals. Using RNA-seq and ChIP-seq we show that BMP/Smad1 regulates dorsal-ventral gene expression in both the endoderm and mesoderm, whereas Wnt/β-catenin acts...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2002) 129 (15): 3645–3656.
Published: 01 August 2002
...Ryan B. Green; Victor Hatini; Katherine A. Johansen; Xue-Jun Liu; Judith A. Lengyel Elongation of the Drosophila embryonic hindgut epithelium occurs by a process of oriented cell rearrangement requiring the genes drumstick ( drm ) and lines ( lin ). The elongating hindgut becomes subdivided...