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Keywords: Hh signaling
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Journal Articles
In collection:
Neural development
Journal: Development
Development (2024) 151 (2): dev202043.
Published: 11 January 2024
... signaling appears to be one of the important regulators. Fgfr2 is expressed in the progenitor cells during tooth root development. Loss of FGF signaling leads to shortened roots with compromised proliferation and differentiation of progenitor cells. Furthermore, Hh signaling is impaired in Gli1-Cre ER...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2022) 149 (23): dev199842.
Published: 7 December 2022
... may contribute to the informational versatility of the conserved Hh signaling pathway. * Present address: Instituto Gulbenkian de Ciência, 2780-156 Oeiras, Portugal. ‡ Authors for correspondence ( david.miguez@uam.es ; fcasfer@upo.es ) Handling Editor: James Briscoe Competing...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (14): 2604–2613.
Published: 15 July 2012
... patterning of ocular tissue and direct guidance of RGC axons. Here, we examine the precise spatial and temporal requirement for Hedgehog (Hh) signaling for intraretinal axon pathfinding and show that Shh acts to pattern the optic stalk in zebrafish but does not guide RGC axons inside the eye directly. We...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2010) 137 (12): 2033–2044.
Published: 15 June 2010
...Dong Yan; Yihui Wu; Yongfei Yang; Tatyana Y. Belenkaya; Xiaofang Tang; Xinhua Lin Hedgehog (Hh) acts as a morphogen in various developmental contexts to specify distinct cell fates in a concentration-dependent manner. Hh signaling is regulated by two conserved cell-surface proteins: Ig/fibronectin...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2005) 132 (13): 3103–3111.
Published: 1 July 2005
... that mouse mutants for two IFT proteins, IFT88 and IFT172, as well as Kif3a, a subunit of mouse kinesin 2, exhibit ventral spinal cord patterning defects that appear to result from reduced hedgehog(Hh) signaling. Although genetic epistasis experiments place IFT proteins downstream of the Hh receptor...
Journal Articles
Journal: Development
Development (2001) 128 (23): 4691–4704.
Published: 1 December 2001
...Ting Chang; Julie Mazotta; Karin Dumstrei; Andra Dumitrescu; Volker Hartenstein We have analyzed the function of the Decapentaplegic (Dpp) and Hedgehog (Hh) signaling pathways in partitioning the dorsal head neurectoderm of the Drosophila embryo. This region, referred to as the anterior brain/eye...