... to environmental stimuli. 16 8 2010 © 2010. daf-12 Dauer formation Developmental timing Heterochronic gene lin-42 Caenorhabditis elegans Animals monitor a variety of environmental cues, including seasonal variation in day length as well as more unpredictable...

... in Caenorhabditis elegans . EMBO J. 25 , 5794 - 5804 . Moss E. G. ( 2007 ). Heterochronic genes and the nature of developmental time . Curr. Biol. 17 , R425 - R434 . Moss E. G. , Tang L. ( 2003 ). Conservation of the heterochronic regulator Lin-28, its developmental expression...

... the heterochronic pathway. We propose daf-12 and other heterochronic genes provide cellular memories of chronological stage for selecting stage-appropriate developmental programs. Endocrine factors could coordinate these stage transitions and specify developmental alternatives. REFERENCES Ambros , V...

...Ann E. Rougvie; Victor Ambros ABSTRACT A hierarchy of heterochronic genes, lin-4, lin-14, lin-28 and lin-29 , temporally restricts terminal differentiation of Caenorhabditis elegans hypodermal seam cells to the final molt. This terminal differentiation event involves cell cycle exit, cell fusion...