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Keywords: Heterochromatin
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Journal Articles
Journal: Development
Series: REVIEW COMMONS TRANSFER
Development (2022) 149 (15): dev200864.
Published: 2 August 2022
... in the establishment of the stably silenced state. We propose that the H3K9me3 blocks formed on the Xi facilitate robust heterochromatin formation in combination with H3K27me3, and that the substantial loss of H3K9me3 caused by SmcHD1 deficiency leads to aberrant distribution of H3K27me3 on the Xi and derepression...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (19): dev174516.
Published: 10 October 2019
...Beste Mutlu; Huei-Mei Chen; Silvia Gutnik; David H. Hall; Sabine Keppler-Ross; Susan E. Mango ABSTRACT During the first hours of embryogenesis, formation of higher-order heterochromatin coincides with the loss of developmental potential. Here, we examine the relationship between these two events...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2019) 146 (19): dev181180.
Published: 20 September 2019
...Maria Ninova; Katalin Fejes Tóth; Alexei A. Aravin ABSTRACT Histone 3 lysine 9 trimethylation (H3K9me3) is a conserved histone modification that is best known for its role in constitutive heterochromatin formation and the repression of repetitive DNA elements. More recently, it has become evident...
Journal Articles
Journal: Development
Development (2018) 145 (23): dev170639.
Published: 4 December 2018
... of the heterochromatin. In a position-effect variegation assay, we found a dominant genetic interaction between sov and HP1a, indicating their functional cooperation in promoting the spread of heterochromatin. An in vivo tethering assay and FRAP analysis revealed that Sov enhances heterochromatin formation by supporting...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2016) 143 (10): 1788–1799.
Published: 15 May 2016
.... , Fuchs , C. , Theis , F. J. and Schotta , G. ( 2015 ). Atrx promotes heterochromatin formation at retrotransposons . EMBO Rep.   16 , 836 - 850 . 10.15252/embr.201439937 Santoni de Sio , F. R. , Massacand , J. , Barde , I. , Offner , S. , Corsinotti...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2015) 142 (10): 1806–1817.
Published: 15 May 2015
... to pericentric heterochromatin during the transition to the first mitosis. This stage is also characterized by a striking kinetochore size asymmetry established by differences in CENP-C protein between the parental genomes. Loss of ATRX results in increased centromeric mitotic recombination, a high frequency...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2013) 140 (19): 4008–4019.
Published: 1 October 2013
... somatic niche. Reprogramming is characterized by chromatin decondensation, reduction in heterochromatin, depletion of linker histones, changes in core histone variants and in histone modification landscapes. From the analysis of mutants in which the gametophyte fate is either expressed ectopically...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2012) 139 (15): 2792–2803.
Published: 1 August 2012
.... 2012 Noncoding RNA Epigenetics Chromatin Kcnq1ot1 Heterochromatin Mouse Genomic imprinting * These authors equally contributed to this work ‡ Author for correspondence ( Kanduri.Chandrasekhar@gu.se ) During the past few years, a large number of studies have focused...
Includes: Supplementary data
Journal Articles
Journal: Development
Development (2002) 129 (17): 3975–3982.
Published: 1 September 2002
...Yannis Jaquet; Marion Delattre; Anne Spierer; Pierre Spierer An increase in the dose of the heterochromatin-associated Su(var)3-7 protein of Drosophila augments the genomic silencing of position-effect variegation. We have expressed a number of fragments of the protein in flies to assign functions...
Journal Articles
Journal: Development
Development (1990) 108 (Supplement): 35–45.
Published: 1 April 1990
...Kenneth D. Tartof; Marilyn Bremer The study of variegating position effects in Drosophila provides a model system to explore the mechanism and material basis for the construction and developmental control of heterochromatin domains and the imprinted genomic structures that they may create...