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1-4 of 4
Keywords: Hereditary hemorrhagic telangiectasia
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Journal Articles
Journal:
Development
Development (2016) 143 (14): 2593–2602.
Published: 15 July 2016
...Elizabeth R. Rochon; Prahlad G. Menon; Beth L. Roman Heterozygous loss of the arterial-specific TGFβ type I receptor, activin receptor-like kinase 1 ( ALK1 ; ACVRL1 ), causes hereditary hemorrhagic telangiectasia (HHT). HHT is characterized by development of fragile, direct connections between...
Includes: Supplementary data
Journal Articles
Circulating Bmp10 acts through endothelial Alk1 to mediate flow-dependent arterial quiescence
Available to Purchase
Journal:
Development
Development (2013) 140 (16): 3403–3412.
Published: 15 August 2013
... no competing financial interests. 5 6 2013 © 2013. Published by The Company of Biologists Ltd 2013 Bmp10 Alk1/Acvrl1 Hereditary hemorrhagic telangiectasia Arteriovenous malformation Zebrafish Flow response Blood flow imparts mechanical forces and distributes...
Includes: Supplementary data
Journal Articles
Interaction between alk1 and blood flow in the development of arteriovenous malformations
Available to PurchasePaola Corti, Sarah Young, Chia-Yuan Chen, Michael J. Patrick, Elizabeth R. Rochon, Kerem Pekkan, Beth L. Roman
Journal:
Development
Development (2011) 138 (8): 1573–1582.
Published: 15 April 2011
... of blood flow in their development, we analyzed AVM development in zebrafish embryos harboring a mutation in activin receptor-like kinase I ( alk1 ), which encodes a TGFβ family type I receptor implicated in the human vascular disorder hereditary hemorrhagic telangiectasia type 2 (HHT2). Our analyses...
Includes: Multimedia, Supplementary data
Journal Articles
Disruption of acvrl1 increases endothelial cell number in zebrafish cranial vessels
Available to PurchaseBeth L. Roman, Van N. Pham, Nathan D. Lawson, Magdalena Kulik, Sarah Childs, Arne C. Lekven, Deborah M. Garrity, Randall T. Moon, Mark C. Fishman, Robert J. Lechleider, Brant M. Weinstein
Journal:
Development
Development (2002) 129 (12): 3009–3019.
Published: 15 June 2002
... dominant disorder, hereditary hemorrhagic telangiectasia type 2, in which disruption of ACVRL1 causes vessel malformations that may result in hemorrhage or stroke. Movies available on-line §Author for correspondence (e-mail: [email protected] ) 1 4 2002 © 2002. 2002 Acvrl1...
Includes: Multimedia, Supplementary data
