...Nicole Prior; Christopher J. Hindley; Fabian Rost; Elena Meléndez; Winnie W. Y. Lau; Berthold Göttgens; Steffen Rulands; Benjamin D. Simons; Meritxell Huch; Allon Klein; Barbara Treutlein ABSTRACT During mouse embryogenesis, progenitors within the liver known as hepatoblasts give rise to adult...

... hepatoblasts by demonstrating that single hepatoblasts contribute to both the hepatocyte and the cholangiocyte lineage in vivo . Together, these data provide new insights into pancreatic, gastric and intestinal development, and point to the existence of a common dorsal pancreas/intestine progenitor as well...

..., and transcriptional programs necessary to form a vertebrate liver. Cholangiocyte Hepatoblast Hepatocyte Liver development Transcription factors The liver controls glycolytic and urea metabolism, blood detoxification and cholesterol levels, while supporting the hematopoietic and digestive systems...

...-mammary syndrome, is specifically expressed in multipotent hepatic progenitor cells,`hepatoblasts', isolated from the developing mouse liver. Tbx3 -deficient hepatoblasts presented severe defects in proliferation as well as uncontrollable hepatobiliary lineage segregation, including the promotion...

... liver Rat Micromagnetic bead Hepatoblast Non-parenchymal cell Two dimensional SDS-PAGE Dipeptidyl peptidase IV Immunofluorescence Histochemical stain Type II liver progenitor cells or oval cells are located within the smallest branches of the intrahepatic biliary tree( Sell, 2001 ). Upon...